Evidence map›Paper›PMID 42290920›Full record

ArticleFrontiers in allergy2026

Food-induced anaphylaxis following skin prick testing: a case report and literature review.

E Novembre, F Mori, C Mastrorilli, Stefania Arasi, Simona Barni, Lucia Caminiti, Riccardo Castagnoli, Mariannita Gelsomino, Mattia Giovannini, Angela Klain and 4 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in allergy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

E NovembreDepartment of Health Sciences, University of Florence, Florence, Italy.
F MoriAllergy Unit, Meyer Children's Hospital IRCCS, Florence, Italy.
C MastrorilliPediatric Department, Pediatric Hospital Giovanni XXIII, AOU Policlinic of Bari, Bari, Italy.
Stefania ArasiTranslational Research in Paediatric Specialities Area, Division of Allergy, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Simona BarniAllergy Unit, Meyer Children's Hospital IRCCS, Florence, Italy.
Lucia CaminitiDepartment of Human Pathology in Adult and Development Age "Gaetano Barresi," Allergy Unit, Department of Pediatrics, AOU Policlinico Gaetano Martino, Messina, Italy.
Riccardo CastagnoliDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.
Mariannita GelsominoDepartment of Life Sciences and Public Health, Pediatric Allergy Unit, University Foundation Policlinico Gemelli IRCCS, Catholic University of the Sacred Heart, Rome, Italy.
Mattia GiovanniniDepartment of Health Sciences, University of Florence, Florence, Italy.
Angela KlainDepartment of Woman, Child and General and Specialized Surgery, University of Campania Luigi Vanvitelli, Naples, Italy.
Lucia LiottiPediatric Unit, Department of Mother and Child Health, Salesi Children's Hospital, Ancona, Italy.
Luca PecoraroDepartment of Experimental Medicine Pediatric Section, University of Salento Hospital "Vito Fazzi," Lecce, Italy.
Francesca SarettaPediatric Department, Latisana-Palmanova Hospital, Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy.
Gian Luigi MarsegliaDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A case of legume-induced anaphylaxis following prick-to-prick (PtP) testing in a 2.5-year-old girl is described. Very few cases of food-induced anaphylaxis following skin prick testing are reported in the literature. Fish and nuts are the most commonly implicated allergens; however, milk, egg, legumes, and vegetables may also be involved. Some potential risk factors have been suggested, including young age, concomitant atopic dermatitis (AD) or asthma, large diameter of the skin test reaction, a history of previous anaphylaxis, and the use of fresh food allergens. The most convincing risk factor reported is the use of PtP testing with fresh, multiple, and often cross-reactive food allergens. When indicated, diagnostic testing should be performed in separate sessions, and the number of PtP tests with fresh foods should therefore be minimized. Physicians should be aware of the potential risk of severe reactions with PtP in certain diagnostic circumstances; therefore, emergency equipment and medications for the treatment of allergic reactions should always be available.

Indexed as

anaphylaxisatopic dermatitis (AD)generalized allergic reactions (GARs)prick-to-prick (PtP)skin prick test (SPT)specific serum IgE (sIgE)systemic reactions (SRs)

Identifiers

PMID42290920
PMCPMC13260392

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.