Evidence map›Paper›PMID 42291195›Full record

ArticleiScience2026

Pyran compound 7r exerts neuroprotective effects against Parkinson's disease via modulating oxidative stress and autophagy.

Rui-Ting Han, Lu Luo, Xin-Jie Zhang, Zi-Jie Wu, Meng-Qin Xie, Xiang-Zhi Zhang, Bao-Qiong Li, Na Feng

Abstract read
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rui-Ting HanSchool of Pharmacy and Food Engineering, Wuyi University, Jiangmen 529000, China.
Lu LuoSchool of Pharmacy and Food Engineering, Wuyi University, Jiangmen 529000, China.
Xin-Jie ZhangSchool of Pharmacy and Food Engineering, Wuyi University, Jiangmen 529000, China.
Zi-Jie WuSchool of Pharmacy and Food Engineering, Wuyi University, Jiangmen 529000, China.
Meng-Qin XieSchool of Pharmacy and Food Engineering, Wuyi University, Jiangmen 529000, China.
Xiang-Zhi ZhangSchool of Pharmacy and Food Engineering, Wuyi University, Jiangmen 529000, China.
Bao-Qiong LiSchool of Pharmacy and Food Engineering, Wuyi University, Jiangmen 529000, China.
Na FengSchool of Pharmacy and Food Engineering, Wuyi University, Jiangmen 529000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aberrant aggregation of α-synuclein (α-syn) represents a key pathological hallmark of Parkinson's disease (PD), with oxidative stress and defective autophagy driving disease progression. In this study, the neuroprotective effects of pyran compound

Indexed as

GeneticsMolecular biologyNeurosciencePharmacology

Identifiers

PMID42291195
PMCPMC13259626

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.