Evidence map›Paper›PMID 42291263›Full record

ArticleiScience2026

Mental health in early pregnancy: Interplay of objectively measured lifestyles, gut microbiota, and metabolomics.

KeKe Guo, Zhengxiao Zhang, Xinyi Zheng, Na Li, Danye Qiu, Zhongying Zhang, Chunhong Zhang, Lingling Li, Haiyan Lin, Chuanhuai Xu and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

KeKe GuoSchool of Public Health, Xiamen University, Xiamen, Fujian 361000, China.
Zhengxiao ZhangCollege of Ocean Food and Biological Engineering, Jimei University, Xiamen, Fujian 361000, China.
Xinyi ZhengSchool of Public Health, Xiamen University, Xiamen, Fujian 361000, China.
Na LiObstetrics and Gynecology, Xiamen Humanity Obstetrics and Gynecology Hospital, Xiamen, Fujian 361000, China.
Danye QiuSchool of Public Health, Xiamen University, Xiamen, Fujian 361000, China.
Zhongying ZhangMedical Laboratory Center, Xiamen Humanity Hospital, Xiamen, Fujian 361000, China.
Chunhong ZhangObstetrics and Gynecology, Yunxiao Maternal and Child Health Hospital, Zhangzhou, Fujian 363000, China.
Lingling LiSchool of Public Health, Xiamen University, Xiamen, Fujian 361000, China.
Haiyan LinSchool of Public Health, Xiamen University, Xiamen, Fujian 361000, China.
Chuanhuai XuSchool of Public Health, Xiamen University, Xiamen, Fujian 361000, China.
Shanshan JiangCollege of Ocean Food and Biological Engineering, Jimei University, Xiamen, Fujian 361000, China.
Xuege JiSchool of Public Health, Xiamen University, Xiamen, Fujian 361000, China.
Mingyue YangCollege of Ocean Food and Biological Engineering, Jimei University, Xiamen, Fujian 361000, China.
Changcan FengCollege of Ocean Food and Biological Engineering, Jimei University, Xiamen, Fujian 361000, China.
Shuhong DengObstetrics and Gynecology, Xiamen Humanity Obstetrics and Gynecology Hospital, Xiamen, Fujian 361000, China.
Xinxin LiObstetrics and Gynecology, Xiamen Humanity Obstetrics and Gynecology Hospital, Xiamen, Fujian 361000, China.
Yiyu WuRadiology Department, Yunxiao Yunling Community Health Service Center, Zhangzhou, Fujian 363000, China.
Lei ZhangState Key Laboratory of Vaccines for Infectious Diseases, School of Public Health, Xiamen University, Xiamen, Fujian 361000, China.
Youliang YaoState Key Laboratory of Vaccines for Infectious Diseases, Xiang an Biomedicine Laboratory, Center for Molecular Imaging and Translational Medicine, Department of Vascular & Tumor Interventional Radiology, The First Affiliated Hospital of Xiamen University, School of Medicine, School of Public Health, Xiamen University, Xiamen, Fujian 361000, China.
Margie DavenportProgram for Pregnancy and Postpartum Health, Physical Activity and Diabetes Laboratory, Faculty of Kinesiology, Sport, and Recreation, Women and Children's Health Research Institute, Alberta Diabetes Institute, University of Alberta, Edmonton, AB T6G 2E1, Canada.
Chenxi CaiState Key Laboratory of Vaccines for Infectious Diseases, School of Public Health, Xiamen University, Xiamen, Fujian 361000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prenatal anxiety symptoms (AS) and depression symptoms (DS) in early pregnancy substantially impact maternal-infant health, but their pathophysiological mechanisms remain unclear. We conducted a multimodal assessment of 161 early-pregnant women. DS exhibited significantly longer standing/sitting durations and shorter nocturnal sleep and nap times (

Indexed as

Clinical findingMetabolomics

Identifiers

PMID42291263
PMCPMC13253093

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.