Evidence map›Paper›PMID 42292068›Full record

ReviewInternational journal of analytical chemistry2026

The Role of Artificial Intelligence in Modern Analytical Chemistry: Current Trends and Future Directions.

Samar H Elagamy, Hemanth Kumar Chanduluru, Reem H Obaydo, Hayam Mahmoud Lotfy

Abstract readReview
In one paragraph

Review in International journal of analytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Samar H ElagamyDepartment of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Tanta University, Tanta, 31111, Egypt, tanta.edu.eg.ORCID https://orcid.org/0000-0003-0181-1713
Hemanth Kumar ChanduluruSRM College of Pharmacy, Faculty of Medical and Health Sciences, SRM Institute of Science and Technology, Kattankulathur Chengalpattu, Tamil Nadu, 603203, India, srmist.edu.in.ORCID https://orcid.org/0000-0003-4814-5201
Reem H ObaydoDepartment of Analytical and Food Chemistry, Faculty of Pharmacy, Ebla Private University, Idlib, Syria.ORCID https://orcid.org/0000-0003-1496-4612
Hayam Mahmoud LotfyDepartment of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Cairo University, El-Kasr El-Aini Street, Cairo, 11562, Egypt, cu.edu.eg.ORCID https://orcid.org/0000-0002-4126-7663

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The integration of artificial intelligence (AI) plays a crucial role in modern analytical chemistry, offering solutions to long-standing challenges. Conventional techniques, such as spectrophotometric analysis and chromatography, often face issues like spectral overlap, matrix interference, and extensive experimental optimization. AI and machine learning (ML) approaches address these limitations by enabling spectral deconvolution, pattern recognition, prediction of retention factors, and automated optimization of separation conditions. Beyond enhancing traditional methods, AI supports the development of innovative analytical platforms. Modern analytical chemistry increasingly relies on smartphone- and paper-based sensors for on-site detection of biomarkers and pollutants. These portable, low-cost systems generate complex datasets requiring advanced computational tools, where AI can improve reliability and sensitivity when validated. AI also plays a vital role in synthesizing and optimizing nanomaterials such as carbon quantum dots (CQDs), accelerating experimental fine-tuning through predictive modeling and optimization algorithms. Moreover, AI facilitates the interpretation of large-scale data, providing deeper insights while reducing human error and analysis time. Despite these advancements, challenges remain regarding model interpretability and the integration of heterogeneous datasets. Addressing these requires explainable ML methods that bridge computational predictions with chemical reasoning. This review highlights current AI applications in chromatographic analysis, drug stability studies, and modern analytical chemistry, discusses implementation challenges, and explores future trends shaping the next generation of intelligent analytical systems.

Indexed as

artificial intelligence (AI)deep learning (DL) machine learning (ML)method development

Identifiers

PMID42292068
PMCPMC13263229

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.