Evidence map›Paper›PMID 42292071›Full record

ArticleJAAD international2026

Political determinants of melanoma: Global inequities in skin cancer care.

Sophia Ma, Tarek Zieneldien, Ali Aljassabi, Janice Kim, Isabella J Tan, Jonas Willmann, Erin Jay G Feliciano, Edward Christopher Dee, Shari Lipner, Jane M Grant-Kels

Abstract read
In one paragraph

Article in JAAD international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sophia MaJohns Hopkins University School of Medicine, Baltimore, Maryland.
Tarek ZieneldienJohns Hopkins University School of Medicine, Baltimore, Maryland.
Ali AljassabiDepartment of Pharmaceutical Science, Taneja College of Pharmacy, University of South Florida. Tampa, Florida.
Janice KimMichigan State University College of Osteopathic Medicine, East Lansing, Michigan.
Isabella J TanRutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey.
Jonas WillmannDepartment of Radiation Oncology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Erin Jay G FelicianoSchool of Medicine and Public Health, Ateneo de Manila University, Pasig City, Philippines.
Edward Christopher DeeDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.
Shari LipnerDepartment of Dermatology, Weill Cornell Medicine, New York, New York.
Jane M Grant-KelsDepartment of Dermatology, University of Connecticut School of Medicine, Farmington, Connecticut.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI FRANCESCA M GANY · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Background: Melanoma outcomes differ across countries, income settings, and skin tones, reflecting not only variable environmental and genetic risks but also upstream political determinants of health that shape exposure, access, and resources. Objective: To apply the 3-I framework (Interests, Ideas, and Institutions) to synthesize global melanoma inequities and identify actionable dermatologic implications. Methods: A narrative review of the literature (1990-2025) examined melanoma, inequities, health-system and political determinants, financing, therapies, and global and low- and middle-income country (LMIC) contexts, mapping sources to the 3-I framework. Results: Interests of governments, payers, and industry determine financing priorities, creating access gaps to immunotherapy, surgery, and pathology, particularly in LMICs and underinsured US populations. Ideas in clinical trials, artificial intelligence tools, and education underrepresent skin of color and LMIC contexts. Institutions, including segregation, colonial legacies, and centralized services, create structural barriers to timely evaluation and treatment. Examples from Australia, the US, India, and African contexts reveal recurring patterns. Conclusions: The 3-I framework (Interests, Ideas, and Institutions) identifies levers (equitable financing expansion, inclusive evidence generation, and institutional reform) through which dermatologists can promote earlier detection and equitable care via total body skin examinations for all skin tones and advocacy for covered, integrated skin cancer screening in primary care and high-risk clinic networks.

Indexed as

artificial intelligenceglobal health inequitieshealth insurancemelanomapolitical determinants of healthregional health disparitiesskin cancerskin cancer preventionskin of colorsocioeconomic statusuninsured

Identifiers

PMID42292071
PMCPMC13264029

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.