Evidence mapPaperPMID 42292390Full record

ReviewFrontiers in immunology2026

Recent advances in characterizing the immune microenvironment and biomarkers of endometrial carcinoma.

Jianhong Ma, Guang Yao, Wei Wang

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jianhong MaThe Department of Obstetrics and Gynecology at the Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou, China.
Guang Yao *The Department of Obstetrics and Gynecology at the First Hospital of Lanzhou University, Lanzhou, China.
Wei Wang *The Department of Obstetrics and Gynecology at the Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study builds upon existing research achievements in bioinformatics to systematically screen a comprehensive set of biomarkers and prognostic models associated with immune infiltration regulation in the tumor microenvironment of endometrial carcinoma. It elucidates the predictive value of these markers and models as well as the oncogenic signaling pathways in which they are involved, thereby providing a theoretical foundation and molecular insights into the characteristics of tumor immune infiltration in endometrial carcinoma. Through a cross-study analysis, five immune-related markers and two gene families consistently reported across multiple investigations were identified. Their clinical prognostic significance was validated, and potential mechanisms underlying their roles in carcinogenesis were proposed. Furthermore, the functional implications of immune infiltrating cells on tumor behavior are summarized, offering valuable guidance for target identification and therapeutic strategy development in future clinical immunopharmacological research.

Indexed as

Biomarkers, TumorEndometrial NeoplasmsTumor MicroenvironmentFemaleHumansPrognosisSignal TransductionBiomarkers, Tumorbiomarkerendometrial carcinomaimmune cellimmune microenvironmentprediction modelrisk score

Identifiers

PMID42292390
PMCPMC13260069

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.