SynthesisFrontiers in neurology
Tuina combined with other therapies for treating insomnia: a systematic review and network meta-analysis.
Synthesis in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Insomnia has a high incidence rate among adults, severely affecting physical and mental health and increasing the risk of multiple diseases. Tuina represents an effective non-pharmacological intervention for insomnia management. Nevertheless, the majority of existing clinical evidence on Tuina for insomnia pertains to its use in conjunction with other modalities, and the relative effectiveness among different combined approaches remains unknown. Accordingly, this network meta-analysis compared the impacts of various Tuina-based combination therapies on patients with confirmed insomnia. Methods: A systematic search was performed across PubMed, Cochrane, Embase, Web of Science, CNKI, VIP, WanFang, and SinoMed electronic databases to identify randomized controlled trials (RCTs) meeting the prespecified criteria. Network meta-analysis was performed using Stata version 16.0. Results: Thirty-four RCTs comprising 2,663 subjects were enrolled, assessing 12 distinct Tuina-based combined interventions. The network meta-analysis revealed that for the outcome of total effective rate, the following combinations were showed a statistically significant difference compared to oral medication ( Conclusion: Tuina-based combination therapies showed a potential advantage over drug monotherapy in enhancing both the Total effective rate and PSQI score for insomnia. Among them, the integrated protocol of Tuina together with Breath guiding and acupoint application ranked highest in the network meta-analysis;however, given that the majority of evidence quality was assessed as low or very low, these findings are exploratory and further verification through high-quality RCTs is needed. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420261344347.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.