Evidence map›Paper›PMID 42293281›Full record

ReviewFrontiers in toxicology2026

Advancing chemical mixture toxicity assessment using advanced in vitro NAMs: current status and future perspectives.

Hyunwoo Kim, Donghyeon Kim, Jinhee Choi

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hyunwoo KimDepartment of Environmental Engineering, University of Seoul, Seoul, Republic of Korea.
Donghyeon KimDepartment of Environmental Engineering, University of Seoul, Seoul, Republic of Korea.
Jinhee ChoiDepartment of Environmental Engineering, University of Seoul, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemical exposure in real-world settings occurs predominantly as mixtures, whereas toxicological assessment has long been shaped by single-substance paradigms. As interest in more human-relevant and mechanistically informative testing strategies has grown, new approach methodologies (NAMs) have been increasingly incorporated into mixture toxicity research. However, the role of advanced

Indexed as

advanced in vitro modelsexposure route-relevant modelsHTS/HCI, 3D tissue modelsmixture toxicitynew approach methodologiesomics technologies

Identifiers

PMID42293281
PMCPMC13258531

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.