Evidence map›Paper›PMID 42293318›Full record

ArticleBrain communications2026

Music processing in behavioural variant frontotemporal dementia and Alzheimer's disease: a functional MRI study.

Jochum J van 't Hooft, Wietske van der Zwaag, Alle Meije Wink, Frederik Barkhof, Rebecca S Schaefer, Jason D Warren, Yolande A L Pijnenburg, Betty M Tijms

Abstract read
In one paragraph

Article in Brain communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jochum J van 't HooftAlzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, 1081 HZ Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0001-6917-5173
Wietske van der ZwaagSpinoza Centre for Neuroimaging, Netherlands Academy for Arts and Sciences, 1105 BK Amsterdam, The Netherlands.
Alle Meije WinkDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Universiteit, 1081 HV Amsterdam, the Netherlands.ORCID https://orcid.org/0000-0002-8197-0118
Frederik BarkhofDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Universiteit, 1081 HV Amsterdam, the Netherlands.
Rebecca S SchaeferHealth, Medical and Neuropsychology Unit, Institute of Psychology, Leiden University, 2300 RB Leiden, The Netherlands.
Jason D WarrenDementia Research Centre, UCL Queen Square Institute of Neurology, University College London, London WC1N 1AR, United Kingdom.
Yolande A L PijnenburgAlzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, 1081 HZ Amsterdam, The Netherlands.
Betty M TijmsAlzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, 1081 HZ Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0002-2612-1797

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Music engages brain regions involved in perceptual, socio-emotional and cognitive functions that may be relatively preserved in individuals with Alzheimer's disease but seem affected early in behavioural variant frontotemporal dementia. The effects of music in dementia are often assessed through observational studies, leaving the neurophysiological underpinnings of music processing in these dementia types unclear. Improved understanding of these mechanisms is relevant because the effectiveness of music therapy may depend on dementia types. In this study we investigated whether patients with behavioural variant frontotemporal dementia and Alzheimer's disease differ in music processing compared with healthy controls. We studied 60 participants (

Indexed as

musicalitymusicophiliamusic perceptionsalience networksupplementary motor area

Identifiers

PMID42293318
PMCPMC13263052

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.