Evidence map›Paper›PMID 42293384›Full record

ArticleMaterials today. Bio2026

Extracellular Vesicle-embedded alginate hydrogel patch for accelerated wound healing.

Won Ho Jang, Van Dat Bui, Van Hieu Duong, Sol Shin, Jungmi Lee, Torsha Ghosh, Chang Hyun Lee, Soyoung Son, Jiyeon Kim, Eun-Cheol Lee and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Won Ho JangSchool of Chemical Engineering, College of Engineering, Sungkyunkwan University (SKKU), Suwon, 16419, Republic of Korea.
Van Dat BuiSchool of Chemical Engineering, College of Engineering, Sungkyunkwan University (SKKU), Suwon, 16419, Republic of Korea.
Van Hieu DuongSchool of Chemical Engineering, College of Engineering, Sungkyunkwan University (SKKU), Suwon, 16419, Republic of Korea.
Sol ShinDepartment of Integrative Biological Sciences and Industry, Sejong University, Seoul, 05006, Republic of Korea.
Jungmi LeeSchool of Chemical Engineering, College of Engineering, Sungkyunkwan University (SKKU), Suwon, 16419, Republic of Korea.
Torsha GhoshSchool of Chemical Engineering, College of Engineering, Sungkyunkwan University (SKKU), Suwon, 16419, Republic of Korea.
Chang Hyun LeeSchool of Chemical Engineering, College of Engineering, Sungkyunkwan University (SKKU), Suwon, 16419, Republic of Korea.
Soyoung SonSchool of Chemical Engineering, College of Engineering, Sungkyunkwan University (SKKU), Suwon, 16419, Republic of Korea.
Jiyeon KimDepartment of MetaBioHealth, School of Medicine, Sungkyunkwan University (SKKU), Suwon, 16419, Republic of Korea.
Eun-Cheol LeeSchool of Chemical Engineering, College of Engineering, Sungkyunkwan University (SKKU), Suwon, 16419, Republic of Korea.
Suk Ho BhangSchool of Chemical Engineering, College of Engineering, Sungkyunkwan University (SKKU), Suwon, 16419, Republic of Korea.
Jae Hyung ParkSchool of Chemical Engineering, College of Engineering, Sungkyunkwan University (SKKU), Suwon, 16419, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The process of skin wound healing is markedly impaired by elevated levels of reactive oxygen species (ROS) and the persistent presence of pro-inflammatory macrophages in the injured tissue. To address these pathological challenges, we herein developed an alginate-based hydrogel patch (EGEV-Gel) engineered for the sustained release of human adipose stem cell-derived extracellular vesicles (hASC-EVs) and epigallocatechin gallate (EGCG). hASC-EVs were incorporated to promote tissue regeneration, while EGCG served as a potent ROS scavenger. In an

Indexed as

Anti-inflammationControlled releaseEpigallocatechin gallateExtracellular vesiclesHydrogelWound healing

Identifiers

PMID42293384
PMCPMC13264183

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.