Evidence map›Paper›PMID 42293776›Full record

ReviewGastro hep advances2026

Breath-Based Diagnostics in Liver Diseases: Dynamic Assessment of Hepatic Metabolic Reserve and Liver Fibrosis.

Nazli Begum Ozturk, Kamran Qureshi, Wing-Kin Syn, Naim Alkhouri

Abstract readReview
In one paragraph

Review in Gastro hep advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nazli Begum OzturkDivision of Gastroenterology and Hepatology, St. Louis University, St. Louis, Missouri.
Kamran QureshiDivision of Gastroenterology and Hepatology, St. Louis University, St. Louis, Missouri.
Wing-Kin SynDivision of Gastroenterology and Hepatology, St. Louis University, St. Louis, Missouri.
Naim AlkhouriClinical Research Institute of Ohio, Cleveland, Ohio.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global burden of chronic liver disease continues to rise, driven largely by metabolic dysfunction-associated steatotic liver disease and alcohol-associated liver disease. Accurate assessment of hepatic fibrosis and metabolic reserve remains central to prognostication and clinical decision-making. While liver biopsy and conventional laboratory-based scoring systems remain standard tools, they provide static or indirect measures of liver function and have important limitations. Breath testing has emerged as a noninvasive, physiologically grounded approach to assess real-time hepatic metabolic capacity. Isotope-based breath tests utilize

Indexed as

Breath TestingChronic Liver DiseaseDynamic Liver FunctionHepatic Metabolic ReserveLIBRA

Identifiers

PMID42293776
PMCPMC13260095

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.