ArticleACS omega2026
Antiaging Effects of Mannose-6-Phosphate through Enhanced Mitochondrial Function and Collagen Remodeling.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aging is closely linked to mitochondrial dysfunction and the deterioration of the extracellular matrix (ECM), especially collagen. Mannose-6-phosphate (M6P), a naturally occurring glycolytic intermediate, has gained attention as a bioactive compound with potential antiaging benefits, modulating cellular metabolism. This study investigates the role of M6P in mitochondrial activity, oxidative stress, autophagy, and collagen remodeling. In vitro experiments with human keratinocytes and dermal fibroblasts revealed that M6P treatment significantly increased ATP, NADH, and NAD
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.