Evidence map›Paper›PMID 42294625›Full record

ArticlemSphere2026

Adaptation of

EricaRose Warwick, Rachel Burt, Jeffrey T Badigian, Daniel Howell, Kyle T Swallow, Chloe Leach, Azeza M Falghoush, Dana K Shaw, Ian T Cadby, Jason M Park

Abstract read
In one paragraph

Article in mSphere, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

EricaRose WarwickDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington, USA.
Rachel BurtBristol Veterinary School, University of Bristol, Bristol, United Kingdom.
Jeffrey T BadigianDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington, USA.
Daniel HowellDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington, USA.
Kyle T SwallowDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington, USA.
Chloe LeachDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington, USA.
Azeza M FalghoushDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington, USA.
Dana K ShawDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington, USA.ORCID 0000-0002-5212-2494
Ian T CadbyBristol Veterinary School, University of Bristol, Bristol, United Kingdom.
Jason M ParkDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington, USA.ORCID 0000-0002-9050-5277

Funding

Tick-Pathogen Interactions: Exploring the Intersection between Stress Responses and ImmunityR01AI162819 · NIAID · WASHINGTON STATE UNIVERSITY · PI SHAW, DANA KATHLEEN · 2022 to 2025
$2.0M
Training in Biotechnology: Emphasis in Protein ChemistryT32GM152310 · NIGMS · WASHINGTON STATE UNIVERSITY · PI Bernd Markus Lange · 2024 to 2026
$1.6M
Tool development for Anaplasma phagocytophilum to understand determinants of infectionR61AI179933 · NIAID · WASHINGTON STATE UNIVERSITY · PI Kelly Ann Brayton, Jason Michael Park · 2024 to 2026
$779k
Anaplasma phagocytophilum modulates the type IV secretion system pilus to achieve tick transmissionR21AI151412 · NIAID · WASHINGTON STATE UNIVERSITY · PI BRAYTON, KELLY ANN · 2020 to 2021
$421k
T4SS effectors and tick tropism in Anaplasma phagocytoliumR21AI154023 · NIAID · WASHINGTON STATE UNIVERSITY · PI BRAYTON, KELLY ANN · 2020 to 2021
$421k
Exploring Tr1-regulated transcription networks underpinning adaptation of pathogenic Anaplasma to the tick hostR21AI178392 · NIAID · WASHINGTON STATE UNIVERSITY · PI PARK, JASON MICHAEL · 2023 to 2024
$379k
NIAID NIH HHS R01 AI162819NIAID NIH HHS R21 AI151412NIAID NIH HHS R21 AI154023NIAID NIH HHS R21 AI178392NIAID NIH HHS R61 AI179933NIGMS NIH HHS T32 GM152310NIH HHS R01AI162819NIH HHS R21AI178392, R21AI154023, R21AI151412, R61AI179933
6 · The paper itself

Abstract

Rickettsial pathogens are strictly dependent on the cellular biology of their hosts for survival and replication. Predominantly transmitted by blood-feeding arthropods, these vector-borne pathogens are forced to adapt between the disparate environments of their mammalian host and arthropod vector. To achieve this, the Rickettsial bacteria

Indexed as

Adaptation, PhysiologicalAnaplasma phagocytophilumBacterial ProteinsGene Expression Regulation, BacterialIxodesAnimalsPromoter Regions, GeneticTranscription, GeneticBacterial ProteinsAnaplasmaAnaplasma phagocytophilumbacterial effectorsIxodesmembrane proteinsT4SS effectorstick-borne diseasetranscriptional regulationtranscription factortype IV secretion system

Identifiers

PMID42294625
PMCPMC13410764

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.