Evidence map›Paper›PMID 42294686›Full record

ArticlemBio2026

Swine acute diarrhea syndrome coronavirus nsp5 induces apoptosis by targeting GATA zinc finger domain-containing protein 2A (GATAD2A/p66α).

Haixin Huang, Xin Wang, Yan Qin, Yuying Li, Jiahan Gang, Xinyu Zhang, Lulu Xie, Yimin Zhou, Qiaoqiong Wang, Wei Chen and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Haixin HuangSchool of Public Health, Beihua University, Jilin City, Jilin Province, China.ORCID 0009-0008-2420-7168
Xin WangJilin Provincial Center for Disease Control and Prevention, Changchun, Jilin Province, China.
Yan QinWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou, Zhejiang, China.
Yuying LiWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou, Zhejiang, China.
Jiahan GangCollege of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, Harbin, China.
Xinyu ZhangWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou, Zhejiang, China.
Lulu XieWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou, Zhejiang, China.
Yimin ZhouWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou, Zhejiang, China.
Qiaoqiong WangWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou, Zhejiang, China.
Wei ChenWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou, Zhejiang, China.
Yuanze SunWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou, Zhejiang, China.
Zaijuan ZhangWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou, Zhejiang, China.
Xianfu KeZhejiang Key Laboratory of High-level Biosafety and Biomedical Transformation, Hangzhou Medical College, Hangzhou, Zhejiang, China.
Tian LanWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou, Zhejiang, China.
Wenchao SunWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou, Zhejiang, China.ORCID 0000-0003-0805-6781

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Swine acute diarrhea syndrome coronavirus (SADS-CoV) causes severe enteric disease in neonatal piglets, resulting in substantial economic losses worldwide. The molecular mechanisms underlying SADS-CoV pathogenesis, particularly how viral proteins modulate host cell death, remain poorly understood. Here, we demonstrated that SADS-CoV infection induces apoptosis

Indexed as

AlphacoronavirusApoptosisCoronavirus InfectionsSwine DiseasesViral Nonstructural ProteinsAnimalsHumansSwineViral Nonstructural ProteinsapoptosisGATAD2Ansp5SADS-CoV

Identifiers

PMID42294686
PMCPMC13343927

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.