SynthesisLasers in surgery and medicine2026
Diode Laser-Assisted Oral Frenectomy as a Modern Alternative: A Systematic Review and Meta-Analysis.
Synthesis in Lasers in surgery and medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
backgroundClinicians frequently use diode laser-assisted oral frenectomy to correct anatomical restrictions in the oral cavity as a minimally invasive alternative. However, evidence for its effect on wound healing and on reducing common postoperative complications remains unclear. This systematic review and meta-analysis aimed to evaluate the clinical efficacy of diode laser-assisted frenectomy compared with the conventional scalpel technique.
methodsThis review adheres to the PRISMA statement, and the protocol is registered in PROSPERO (CRD420251050170). A comprehensive electronic and manual search identified comparative studies of diode laser vs. scalpel frenectomy from January 2015 to December 2025. The analysis pooled the primary outcomes (postoperative discomfort, intraoperative hemorrhage, and wound healing) with 95% confidence intervals (CI) using a random-effects model. Heterogeneity assessment used the I
resultsFourteen studies met the inclusion criteria. The meta-analysis showed that the diode laser reduced postoperative pain on day 1 (SMD = -1.73; 95% CI: -2.70 to -0.77) and day 7 (SMD = -1.84; 95% CI: -2.78 to -0.90), compared with the scalpel. The diode laser also reduced intraoperative hemorrhage (SMD = -1.97; 95% CI: -2.89 to -1.05). Wound healing on day 7 did not differ significantly between groups.
conclusionsThis meta-analysis indicates that diode laser-assisted frenectomy reduces postoperative pain, significantly. In addition, the laser group experienced less intraoperative hemorrhage and better wound healing at 7 day. Future clinical trials should standardize wound-healing indices, define uniform follow-up intervals, and incorporate cost-effectiveness analyses.
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