Evidence mapPaperPMID 42297381Full record

ReviewThe Journal of international medical research2026

Pulmonary fibrosis: Emerging targets and novel therapeutics.

Yucen Sun, Li Li

Abstract readReview
In one paragraph

Review in The Journal of international medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yucen SunDepartment of Respiratory Disease, Shanghai Baoshan District Hospital of Integrated Traditional Chinese and Western Medicine (Baoshan Hospital Affiliated to Shanghai University of Traditional Chinese Medicine), China.ORCID 0009-0006-7907-8733
Li LiDepartment of Respiratory Disease, Shanghai Baoshan District Hospital of Integrated Traditional Chinese and Western Medicine (Baoshan Hospital Affiliated to Shanghai University of Traditional Chinese Medicine), China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary fibrosis, particularly idiopathic pulmonary fibrosis, is a progressive and fatal interstitial lung disease with limited curative therapies. This narrative review provides a concise overview of emerging molecular targets and novel therapeutic strategies for pulmonary fibrosis, including mesenchymal stem cell therapy and nanomaterial-based inhalation systems, focusing on their mechanisms, preclinical evidence, and clinical potential. We highlight critical challenges in translating preclinical discoveries into clinical benefit, such as animal model limitations and patient heterogeneity, and outline future research priorities. Notably, this review is not a systematic review; it does not include formal meta-analysis or a comprehensive literature search following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, which may have introduced selection bias. Thus, findings should be interpreted with appropriate caution.

Indexed as

Idiopathic Pulmonary FibrosisMesenchymal Stem Cell TransplantationMolecular Targeted TherapyPulmonary FibrosisAnimalsHumansMesenchymal Stem Cellsmesenchymal stem cell therapynano-inhalation therapypathogenesisPulmonary fibrosistherapeutic targets

Identifiers

PMID42297381
PMCPMC13269959

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.