Evidence map›Paper›PMID 42297897›Full record

ArticleJournal of exposure science & environmental epidemiology2026

Long-term outdoor air pollution and risk of ovarian and endometrial cancers in a large prospective cohort.

Samantha Ammons, Jared A Fisher, Jessica M Madrigal, Lauren M Hurwitz, Joel D Kaufman, Alexandra J White, Britton Trabert, Debra T Silverman, Katie M Applebaum, Megan A Clarke and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of exposure science & environmental epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Samantha AmmonsOccupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics (DCEG), National Cancer Institute (NCI), National Institutes of Health (NIH), Rockville, MD, USA.
Jared A FisherOccupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics (DCEG), National Cancer Institute (NCI), National Institutes of Health (NIH), Rockville, MD, USA.
Jessica M MadrigalOccupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics (DCEG), National Cancer Institute (NCI), National Institutes of Health (NIH), Rockville, MD, USA. jmadri1@uis.edu.
Lauren M HurwitzOccupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics (DCEG), National Cancer Institute (NCI), National Institutes of Health (NIH), Rockville, MD, USA.
Joel D KaufmanDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, USA.
Alexandra J WhiteEpidemiology Branch, Chronic Disease Epidemiology Group, National Institute of Environmental Health Sciences, National Institutes of Health, Durham, NC, USA.
Britton TrabertDepartment of Obstetrics and Gynecology, Fox Spencer Eccles School of Medicine, University of Utah, and Huntsman Cancer Institute at the University of Utah, Salt Lake City, UT, USA.
Debra T SilvermanOccupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics (DCEG), National Cancer Institute (NCI), National Institutes of Health (NIH), Rockville, MD, USA.
Katie M ApplebaumDepartment of Environmental and Occupational Health, The George Washington University, Milken Institute School of Public Health, Washington, DC, USA.
Megan A ClarkeClinical Genetics Branch, DCEG, NCI, NIH, Rockville, MD, USA.
Rena R JonesOccupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics (DCEG), National Cancer Institute (NCI), National Institutes of Health (NIH), Rockville, MD, USA.ORCID http://orcid.org/0000-0003-1294-1679

Funding

Transportation, air quality, and health: a community-centered study of road pricing in Washington, DC.P20ES036775 · NIEHS · GEORGE WASHINGTON UNIVERSITY · PI Benjamin A Cash · 2024 to 2026
$4.9M
NIEHS NIH HHS P20 ES036775
6 · The paper itself

Abstract

backgroundOutdoor air pollution is a known human carcinogen, but studies of female reproductive malignancies other than breast cancer remain limited.

objectiveWe evaluated associations between outdoor air pollutants and risk of two gynecologic cancers

methodsUsing nationwide spatiotemporal models, we estimated outdoor residential fine particulate matter (PM

resultsWe found no relationships with risk of either cancer overall. PM SIGNIFICANCE: We demonstrated modest relationships between air pollutants and risk of endometrial and ovarian cancers for select geographies, neighborhood characteristics, and histologic subtypes. Our findings indicate that future studies should evaluate region-specific factors, including co-varying pollutant distributions. IMPACT STATEMENT: Research on endometrial and ovarian cancers has primarily focused on risk factors such as body mass index and exposure to exogenous and endogenous hormones, particularly unopposed estrogen. We identified suggestive associations between these two cancers and outdoor air pollution exposures, specifically PM

Indexed as

Ambient air pollutionEndometrial cancerNO2Ovarian cancerPM2.5

Identifiers

PMID42297897

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.