Evidence map›Paper›PMID 42297939›Full record

ArticleScientific reports2026

Biosynthesis of ecofriendly antibacterial nanoparticles with healing effects in a murine diabetic skin infection model.

Eman A Mustafa, Hanady G Nada, Walaa A Eraqi, Rehab N Shamma, Hala N Elhifnawi, Nourtan F Abdeltawab

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In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eman A MustafaPostgraduate Program in Microbiology and Immunology, Faculty of Pharmacy, Cairo University, Cairo, Egypt. dr.eman.ashraf86@gmail.com.
Hanady G NadaDrug Radiation Research Department, National Center for Radiation Research and Technology, Egyptian Atomic Energy Authority, Cairo, Egypt.
Walaa A EraqiDepartment of Microbiology and Immunology, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt.
Rehab N ShammaDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt.
Hala N ElhifnawiDrug Radiation Research Department, National Center for Radiation Research and Technology, Egyptian Atomic Energy Authority, Cairo, Egypt.
Nourtan F AbdeltawabDepartment of Microbiology and Immunology, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt. nourtan.abdeltawab@pharma.cu.edu.eg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes mellitus is a global concern with complications including recurrent skin infections and poor wound healing. The involvement of multidrug-resistant bacteria (MDR) in skin infections renders them challenging. Nanoparticles such as silver, zinc oxide, and chitosan-based nanoparticles offer a promise for combating the growing threat of MDR bacteria by employing unique mechanisms that bypass recognized antibiotic resistance pathways. Therefore, this study reports the eco-friendly synthesis of silver (AgNPs), zinc oxide (ZnONPs), and chitosan-tripolyphosphate nanoparticles (Cs-TPP-NPs) using green tea extract (GTE) and gamma irradiation. AgNPs exhibited the highest antibacterial and antibiofilm efficacy among the tested preparations, as reflected by their lowest minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values against four bacterial strains associated with diabetic foot ulcers, including Pseudomonas aeruginosa, Escherichia coli, methicillin-resistant Staphylococcus aureus (MRSA), and Streptococcus pyogenes. The killing activity of AgNPs was fast acting against all tested bacteria with > 10 log

Indexed as

Anti-Bacterial AgentsMetal NanoparticlesSkin Diseases, BacterialWound HealingAnimalsBiofilmsChitosanDiabetes Mellitus, ExperimentalDisease Models, AnimalMiceMicrobial Sensitivity TestsPlant ExtractsSilverAnti-Bacterial AgentsChitosanPlant ExtractsSilverAntibacterial activityDiabetes mellitusDiabetic skin infectionsGamma radiationGreen tea

Identifiers

PMID42297939
PMCPMC13269799

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.