ReviewCommunications biology2026
Recent advances in Mpox across innate immunity, evasion, and clinical outcomes.
Review in Communications biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Recent mpox outbreaks have shown that disease severity cannot be explained by viral burden alone but is instead closely linked to the host immune response. This review synthesizes current evidence on the genomic diversity of monkeypox virus (MPXV), innate immune sensing, inflammatory pathways, immune evasion, and therapeutic strategies. We examine the key host determinants of disease outcome, including interferon signaling competence, inflammasome regulation, and natural killer cell function, together with the clinical manifestations seen in immunocompromised populations. By integrating molecular and clinical perspectives, this review helps explain the heterogeneity of mpox and informs the management of high-risk populations.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.