Evidence map›Paper›PMID 42298229›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026

Health-related quality of life in young pediatric cancer survivors: The role of sarcopenia.

Andres Marmol-Perez, Esther Ubago-Guisado, Cristina Cadenas-Sanchez, Andrea Rodriguez-Solana, Francisco J Llorente-Cantarero, Juan Francisco Pascual-Gázquez, Daniel Moreira-Gonçalves, Jorge Mota, Kirsten K Ness, Jonatan R Ruiz and 1 more

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In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Andres Marmol-PerezDepartment of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS), University of Granada, 18011, Granada, Spain. andresmarmol.imas12@h12o.es.
Esther Ubago-GuisadoDepartment of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS), University of Granada, 18011, Granada, Spain. estherug@ugr.es.
Cristina Cadenas-SanchezDepartment of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS), University of Granada, 18011, Granada, Spain.
Andrea Rodriguez-SolanaDepartment of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS), University of Granada, 18011, Granada, Spain.
Francisco J Llorente-CantareroCIBER de Fisiopatología de La Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029, Madrid, Spain.
Juan Francisco Pascual-GázquezServicio de Hematología y Oncología Infantil y del Adolescente. Unidad de Gestión Clínica de Pediatría y Cirugía Pediátrica. Hospital Universitario Virgen de Las Nieves, Granada, Spain.
Daniel Moreira-GonçalvesFaculty of Sport, Research Center in Physical Activity, Health and Leisure, University of Porto, Porto, Portugal.
Jorge MotaFaculty of Sport, University of Porto, Porto, Portugal.
Kirsten K NessDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
Jonatan R RuizDepartment of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS), University of Granada, 18011, Granada, Spain.
Luis Gracia-MarcoDepartment of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS), University of Granada, 18011, Granada, Spain.

Funding

Ministerio de Ciencia e Innovación PID2020-117302RA-I00
6 · The paper itself

Abstract

purposeSarcopenia is a prevalent musculoskeletal complication after pediatric cancer, and its association with health-related quality of life (HRQoL) remains unknown. This study aimed to investigate health-related quality of life (HRQoL) differences according to sarcopenia status in young pediatric cancer survivors, and determined if these differences were distinct by sex.

methodsThis cross-sectional study included 116 pediatric cancer survivors (12.1 ± 3.3 years old). Muscle strength was evaluated by handgrip strength test, while appendicular lean mass index (ALMI, kg/m

resultsOnly female survivors without sarcopenia had significantly better total HRQoL (-0.3 [95% CI: -0.8 to 0.2] vs. 1.5 [95% CI: -2.1 to -0.8]), physical HRQoL (-0.3 [95% CI: -0.8 to 0.2] vs. -1.6 [95% CI: -2.3 to -0.9]), psychosocial HRQoL (-0.2 [95% CI: -0.7 to 0.3] vs. -1.2 [95% CI: -1.8 to -0.6]) and school HRQoL (-0.1 [95% CI: -0.6 to 0.4] vs. -1.3 [95% CI: -2.0 to -0.7]) than female survivors with sarcopenia confirmed.

conclusionMost HRQoL domains are similar across sarcopenia status in young pediatric cancer survivors. However, female survivors without sarcopenia seem to have better HRQoL Z-score than those with sarcopenia.

Indexed as

Cancer SurvivorsNeoplasmsQuality of LifeSarcopeniaAbsorptiometry, PhotonAdolescentChildCross-Sectional StudiesFemaleHand StrengthHumansMaleMuscle StrengthSex FactorsChildhood cancerExerciseMuscular healthRehabilitationWell-being

Identifiers

PMID42298229
PMCPMC13269377

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.