Evidence map›Paper›PMID 42298512›Full record

ArticleBMC psychiatry2026

Proactive consultation-liaison-services (CL): comparing PHQ-4 screening with traditional referral pathways in medical inpatients - a prospective comparative pilot study.

Paul Köbler, Linda Wilfert, Alexander Dechêne, Eva K Krauß-Köstler, Christiane Waller, Barbara Stein

Abstract readComparative Study
In one paragraph

Article in BMC psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Paul KöblerDepartment of Psychosomatic Medicine and Psychotherapy, Paracelsus Medical University, Nuremberg General Hospital, Prof.-Ernst-Nathan-Str. 1, 90419, Nuremberg, Germany. paul.koebler@klinikum-nuernberg.de.
Linda WilfertDepartment of Psychosomatic Medicine and Psychotherapy, Paracelsus Medical University, Nuremberg General Hospital, Prof.-Ernst-Nathan-Str. 1, 90419, Nuremberg, Germany.
Alexander DechêneDepartment of Internal Medicine 6, Gastroenterology/Hepatology/Endocrinology, Paracelsus Medical University, Nuremberg General Hospital, Nuremberg, Germany.
Eva K Krauß-KöstlerDepartment of Psychosomatic Medicine and Psychotherapy, Paracelsus Medical University, Nuremberg General Hospital, Prof.-Ernst-Nathan-Str. 1, 90419, Nuremberg, Germany.
Christiane WallerDepartment of Psychosomatic Medicine and Psychotherapy, Paracelsus Medical University, Nuremberg General Hospital, Prof.-Ernst-Nathan-Str. 1, 90419, Nuremberg, Germany.
Barbara SteinDepartment of Psychosomatic Medicine and Psychotherapy, Paracelsus Medical University, Nuremberg General Hospital, Prof.-Ernst-Nathan-Str. 1, 90419, Nuremberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPsychiatric comorbidities are highly prevalent among general hospital inpatients but often remain undetected when mental health referrals rely solely on clinical judgment. Systematic screening may improve identification, yet comparative evidence using structured diagnostic interviews remains limited. The study evaluates diagnostic confirmation rate of systematic PHQ-4 screening versus clinician-initiated referral in identifying psychiatric comorbidities among medical inpatients.

methodsIn this quasi-experimental pilot study, systematic screening using the Patient Health Questionnaire-4 (PHQ-4) was implemented on one medical ward (n = 127 admissions), while two comparable wards followed treatment as usual (TAU; n = 267 admissions), with psychosomatic consultations initiated by medical staff based on clinical judgment. Patients screening positive (PHQ-4 ≥ 6 or subscale ≥ 4) were referred for consultation. All referred patients underwent structured diagnostic assessment using the Mini-DIPS interview. Primary outcomes were the proportion of referred patients with a confirmed psychiatric diagnosis (diagnostic confirmation rate) and overall identification rates. Secondary outcomes included time from admission to referral and consultation, as well as treatment recommendations and their uptake.

resultsAmong interviewed patients, screening was associated with a numerically higher rate of diagnostic confirmation than TAU (11/13, 84.6% vs. 8/14, 57.1%), although this difference did not reach statistical significance. A higher proportion of admissions with confirmed psychiatric disorders was observed in the screening group (11/127, 8.7%) compared with TAU (8/267, 3.0%). Referral rates were higher in the screening group (21/127, 16.5% vs. 22/267, 8.2%), and time to consultation was shorter (median 1 vs. 3.5 days). Depressive and anxiety disorders predominated. Follow-up consultation showed high adherence, whereas uptake of inpatient treatment was low.

conclusionsSystematic PHQ-4 screening was associated with higher detection of psychiatric comorbidities and earlier consultation-liaison involvement, suggesting that clinician-initiated referral alone may miss substantial psychiatric morbidity. However, given the quasi-experimental design and limited sample size, the findings should be interpreted cautiously. Larger randomized studies are needed to evaluate implementation and patient outcomes.

Indexed as

InpatientsMass ScreeningMental DisordersReferral and ConsultationAdultAgedComorbidityFemaleHumansMaleMiddle AgedPatient Health QuestionnairePilot ProjectsProspective StudiesAnxietyConsultation-liaisonDepressionDiagnosisHospitalizationInpatientsScreening

Identifiers

PMID42298512
PMCPMC13274105

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.