ArticleAME case reports2026
Fulminant cardiovascular collapse after acute pancreatitis: a case report of non-alcoholic Shoshin beriberi and literature review.
Article in AME case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Shoshin beriberi-fulminant cardiogenic shock caused by thiamine deficiency-is rare in adults and is rarely reported after acute pancreatitis has been treated with long‑term parenteral nutrition (PN). Timely thiamine administration is curative, but the diagnosis is often delayed, and patients may perish before metabolic therapy takes effect. Case Description: A previously healthy 25-year-old man developed refractory shock 2 months into PN for necrotizing pancreatitis. His lactate concentration was 17.4 mmol·L Conclusions: By demonstrating that VA-ECMO can preserve end-organ perfusion until high-dose thiamine reverses fulminant beriberi, this adult case extends the clinical spectrum of thiamine deficiency shock. In practice, diagnosis hinges on a high index of suspicion and simple bedside cues, including prolonged poor intake or PN without vitamin supplementation, otherwise unexplained hyperlactatemia, and subtle neurological signs, such as diplopia, prompting early empirical intravenous thiamine treatment.
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