Evidence mapPaperPMID 42299535Full record

ReviewMedicine2026

Past, present, and future of thermogenic fat research: A bibliometric analysis from 2000 to 2023.

Haiyan Xie, Lan Chen, Boyuan Long, Xudong Song, Mingsheng Jiang, Ziyi Song

Abstract readReview
In one paragraph

Review in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Haiyan XieGuangxi Key Laboratory of Animal Breeding, Disease Control and Prevention, College of Animal Science and Technology, Guangxi University, Nanning, China.
Lan Chen
Boyuan Long
Xudong Song
Mingsheng Jiang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThermogenic fat plays a crucial role in regulating energy metabolism and improving obesity-related metabolic diseases. However, a systematic analysis of the research trends and hotspots in the field of thermogenic fat is lacking. This study aimed to fill this gap by employing bibliometric methods to analyze the global research landscape of thermogenic fat from 2000 to 2023.

methodsA systematic search was conducted in the Web of Science Core Collection to retrieve publications related to thermogenic fat. Various bibliometric tools (HistCite, CiteSpace, and VOSviewer) were used to analyze and visualize the data, including annual publication trends, geographical distribution, institutional and author contributions, citation analysis, and keyword analysis.

resultsA comprehensive search yielded a total of 5246 English-language articles, revealing a significant upward trend in the number of publications focused on thermogenic fat over the past 24 years. The United States stands out as the most productive country, with Harvard University emerging as the leading research institution in this field. Bruce M. Spiegelman was identified as a pivotal figure in advancing thermogenic fat research. The journals that have published the highest number of articles in this field include Molecular Metabolism, Journal of Biological Chemistry, and Scientific Reports, with Cell Metabolism receiving the highest number of citations. The primary research keywords cluster into 9 distinct categories, with the most frequently occurring terms being "obesity," "brown adipose tissue," "thermogenesis," "brown adipocytes," "energy expenditure," "browning," "UCP1," "beige fat," and "type 2 diabetes." Notably, white fat browning and beige fat have emerged as cutting-edge research trends.

conclusionThis investigation provides a comprehensive overview of the global research trends in thermogenic fat through bibliometric analysis. Enhanced insights into the historical development and evolutionary trajectory of this field offer a novel perspective on potential future research avenues. The findings of this study are poised to serve as an invaluable resource for researchers, thereby fostering continued advancement in the study of thermogenic fat.

Indexed as

BibliometricsBiomedical ResearchThermogenesisAnimalsEnergy MetabolismHumansObesitybeige fatbibliometric analysisbrown fatobesitythermogenic fat

Identifiers

PMID42299535
PMCPMC13268563

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.