Evidence map›Paper›PMID 42299891›Full record

ArticleFEBS letters2026

PARK(ing) time-How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease.

Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FEBS letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kamila ZientaraDepartment of Cell Biology and Imaging, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Krakow, Poland.ORCID https://orcid.org/0009-0006-2200-1516
Kinga SkoczekDepartment of Cell Biology and Imaging, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Krakow, Poland.ORCID https://orcid.org/0009-0003-1212-8060
Elzbieta PyzaDepartment of Cell Biology and Imaging, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Krakow, Poland.ORCID https://orcid.org/0000-0003-1503-9533
Milena DamulewiczDepartment of Cell Biology and Imaging, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Krakow, Poland.ORCID https://orcid.org/0000-0002-1766-8328

Funding

Narodowe Centrum Nauki Sonata bis. no. 2022/46/E/NZ3/00095
6 · The paper itself

Abstract

Sleep and circadian disruptions are early symptoms of Parkinson's disease (PD), which is one of the most common neurodegenerative disorders. However, PD has an idiopathic origin, and the factors accelerating the progression of symptoms are not fully understood. One genetic factor associated with PD is a mutation in the parkin gene, which impairs mitophagy and increases oxidative stress. In this research, we used Drosophila melanogaster as a model of PD, employing both a park

Indexed as

Biological ClocksCircadian ClocksDrosophila melanogasterDrosophila ProteinsParkinson DiseaseUbiquitin-Protein LigasesAnimalsCircadian RhythmDisease Models, AnimalMutationNeuronsOxidative StressReactive Oxygen SpeciesDrosophila Proteinspark protein, DrosophilaReactive Oxygen SpeciesUbiquitin-Protein Ligasescircadian clockDrosophila melanogasteroxidative stressParkinson's disease

Identifiers

PMID42299891
PMCPMC13404150

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.