ArticleJournal of medicinal chemistry2026
Mechanistic Exploration of Half-Sandwich Iridium(III) Anticancer Compounds through Integrated Cellular, Proteomic, and In Vivo Analyses.
Pavel Štarha, Jaroslava Friedecká, Renata Héžová, Ondřej Bárta, Rea Jarošová, Josef Mašek, Ivan Nemec, David Milde, Adam Novobilský, Ladislav Novotný and 5 more
Abstract read
In one paragraphArticle in Journal of medicinal chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
15 authors.
Pavel ŠtarhaDepartment of Inorganic Chemistry, Faculty of Science, Palacký University Olomouc, 17. listopadu 12, 77146 Olomouc, Czech Republic.ORCID 0000-0003-0422-045X Jaroslava FriedeckáLaboratory of Growth Regulators, Institute of Experimental Botany of the Czech Academy of Sciences, and Faculty of Science, Palacký University, Šlechtitelů 27, 783 71 Olomouc, Czech Republic.ORCID 0000-0001-8030-6736 Renata HéžováDepartment of Pharmacology and Toxicology, Veterinary Research Institute, Hudcova 296/70, 62100 Brno, Czech Republic.
Ondřej BártaDepartment of Inorganic Chemistry, Faculty of Science, Palacký University Olomouc, 17. listopadu 12, 77146 Olomouc, Czech Republic.ORCID 0000-0002-0982-399X Rea JarošováDepartment of Pharmacology and Toxicology, Veterinary Research Institute, Hudcova 296/70, 62100 Brno, Czech Republic.
Josef MašekDepartment of Pharmacology and Toxicology, Veterinary Research Institute, Hudcova 296/70, 62100 Brno, Czech Republic.
Ivan NemecDepartment of Inorganic Chemistry, Faculty of Science, Palacký University Olomouc, 17. listopadu 12, 77146 Olomouc, Czech Republic.ORCID 0000-0003-3231-7849 David MildeDepartment of Analytical Chemistry, Faculty of Science, Palacký University Olomouc, 17. listopadu 12, 77146 Olomouc, Czech Republic.
Adam NovobilskýDepartment of Pharmacology and Toxicology, Veterinary Research Institute, Hudcova 296/70, 62100 Brno, Czech Republic.
Ladislav NovotnýDepartment of Veterinary Sciences, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences, Kamýcká 129, 16500 Prague, Czech Republic.ORCID 0000-0002-2222-1061 Jaroslav OndrušDepartment of Pharmacology and Toxicology, Veterinary Research Institute, Hudcova 296/70, 62100 Brno, Czech Republic.
Slavomíra ŠterbinskáDepartment of Inorganic Chemistry, Faculty of Science, Palacký University Olomouc, 17. listopadu 12, 77146 Olomouc, Czech Republic.ORCID 0009-0000-3766-6015 Nicol StrakováDepartment of Pharmacology and Toxicology, Veterinary Research Institute, Hudcova 296/70, 62100 Brno, Czech Republic.
René LenobelLaboratory of Growth Regulators, Institute of Experimental Botany of the Czech Academy of Sciences, and Faculty of Science, Palacký University, Šlechtitelů 27, 783 71 Olomouc, Czech Republic.ORCID 0000-0001-7387-0056 Jan HošekDepartment of Pharmacology and Toxicology, Veterinary Research Institute, Hudcova 296/70, 62100 Brno, Czech Republic.ORCID 0000-0003-0975-1671 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
New half-sandwich iridium(III) compounds [Ir(η
Indexed as
Antineoplastic AgentsCoordination ComplexesIridiumAnimalsApoptosisCell Line, TumorHumansMiceOxidative StressProteomicsAntineoplastic AgentsCoordination ComplexesIridium
Identifiers
PMID42300762
PMCPMC13370875
What Socratic holds
Textmetadata
LicenceCC BY
Read underepoch 390