Evidence map›Paper›PMID 42301565›Full record

ArticleJournal of medical ultrasonics (2001)2026

Influence of airway pressure and fibrosis on lung surface shear wave elastography.

Yuki Kawakami, Kensuke Nakamura, Hironobu Yasui, Keisuke Aoshima, Noboru Sasaki, Nozomu Yokoyama, Mitsuyoshi Takiguchi

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Article in Journal of medical ultrasonics (2001), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuki KawakamiLaboratory of Veterinary Internal Medicine, Department of Veterinary Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, N18 W9, Sapporo, Hokkaido, 060-0818, Japan.
Kensuke NakamuraLaboratory of Veterinary Internal Medicine, Department of Veterinary Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, N18 W9, Sapporo, Hokkaido, 060-0818, Japan. nken@vetmed.hokudai.ac.jp.ORCID http://orcid.org/0000-0002-1010-3228
Hironobu YasuiLaboratory of Radiation Biology, Department of Veterinary Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, N18 W9, Sapporo, Hokkaido, 060-0818, Japan.
Keisuke AoshimaLaboratory of Comparative Pathology, Faculty of Veterinary Medicine, Hokkaido University, N18 W9, Sapporo, Hokkaido, 060-0818, Japan.
Noboru SasakiHokkaido University Veterinary Teaching Hospital, N19 W10, Sapporo, Hokkaido, 080-0819, Japan.
Nozomu YokoyamaLaboratory of Veterinary Internal Medicine, Department of Veterinary Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, N18 W9, Sapporo, Hokkaido, 060-0818, Japan.
Mitsuyoshi TakiguchiLaboratory of Veterinary Internal Medicine, Department of Veterinary Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, N18 W9, Sapporo, Hokkaido, 060-0818, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLung ultrasound is widely used in clinical practice, but B-mode findings often lack disease specificity. Shear wave elastography (SWE) enables quantitative assessment of tissue elasticity and may help overcome this limitation. This study aimed to evaluate whether SWE can be used to detect lung surface changes associated with airway pressure and pulmonary fibrosis.

methodsEx vivo porcine lungs (n = 3) were used to examine the effects of airway pressure. Airway pressure was adjusted to 10, 20, and 30 cmH

resultsIn porcine lungs, SWS increased with airway pressure and showed a strong positive correlation. In the radiation-induced fibrosis model, irradiated lungs had significantly higher SWS than non-irradiated lungs. Histopathology confirmed increased fibrosis and reduced air without inflammation. Multiple regression showed a significant association between fibrosis and SWS.

conclusionLung surface SWE detected changes related to airway pressure and pulmonary fibrosis. SWS increased with both, although other factors, such as lung reduction in air content and tensile stress, can also affect measurements.

Indexed as

Airway pressureLung surfacePulmonary fibrosisShear wave elastography

Identifiers

PMID42301565

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.