ReviewGeroScience2026
Promoting healthy aging in occupational settings: satisfaction with life as a strategic target in the Semmelweis-EUniWell framework.
Review in GeroScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
19 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The growing burden of aging-related disease and functional decline across Europe underscores the urgent need to optimize aging trajectories rather than simply extend lifespan. Achieving this goal requires identifying modifiable determinants that shape biological, psychological, and functional aging across the life course. Satisfaction with life (SWL) is emerging as one such integrative factor, linking adaptive capacity, resilience, and long-term healthspan outcomes. In this conceptual and translational paper, we integrate evidence from geroscience, psychology, and occupational health to position SWL as both a marker and a potentially modifiable determinant of healthspan. We review biological, psychological, and social mechanisms linking SWL to aging processes, including cardiovascular and inflammatory regulation, neural and affective processing, psychological resilience and reserve, and social integration and generativity. Collectively, these pathways suggest that SWL reflects the functional integrity of adaptive systems that shape vulnerability to age-related functional decline. We further argue that occupational settings represent a uniquely powerful and scalable context for targeting SWL, given their sustained influence on behavior, stress exposure, social roles, and meaning across adulthood. Building on this framework, we discuss the Semmelweis Study, a large prospective workplace-based cohort, together with the Semmelweis-EUniWell Workplace Health Promotion Program, as an integrated model for translating geroscience-informed insights into structured interventions. Such workplace health promotion programs can target core psychological capacities-including savoring, self-regulation, creative and executive efficiency, and resilience-that are closely linked to adaptive capacity and aging-related outcomes. Finally, we discuss implications for geroscience, public health, and policy, highlighting how embedding SWL as a strategic target within workplace systems may contribute to extending healthspan, strengthening workforce sustainability, and reducing the societal burden of population aging. Conceptualizing satisfaction with life not merely as a subjective outcome but as a dimension of biological aging and adaptive resilience opens new avenues for intervention at the interface of geroscience and real-world systems.
Indexed as
Identifiers
42301612What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.