In one paragraphArticle in ACS medicinal chemistry letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
12 authors.
Temitayo O Alegbejo PriceCenter for the Research and Advancement in Fragments and Molecular Targets (CRAFT), School of Pharmaceutical Sciences at Ribeirao Preto, University of São Paulo, Ribeirão Preto 14040-903, SP, Brazil.ORCID https://orcid.org/0000-0002-8750-0635 Daniel G SilvaCenter for the Research and Advancement in Fragments and Molecular Targets (CRAFT), School of Pharmaceutical Sciences at Ribeirao Preto, University of São Paulo, Ribeirão Preto 14040-903, SP, Brazil.ORCID https://orcid.org/0000-0001-8879-456X Miguel M VaidergornCenter for the Research and Advancement in Fragments and Molecular Targets (CRAFT), School of Pharmaceutical Sciences at Ribeirao Preto, University of São Paulo, Ribeirão Preto 14040-903, SP, Brazil.ORCID https://orcid.org/0000-0003-2343-2888 Beatriz S AugustoCenter for the Research and Advancement in Fragments and Molecular Targets (CRAFT), School of Pharmaceutical Sciences at Ribeirao Preto, University of São Paulo, Ribeirão Preto 14040-903, SP, Brazil.
An MatheeussenLaboratory of Microbiology, Parasitology and Hygiene (LMPH), Infla-Med Centre of Excellence, University of Antwerp, Universiteitsplein 1, Antwerp 2610, Wilrijk, Belgium.ORCID https://orcid.org/0000-0002-7507-1634 Natascha Van PeltLaboratory of Microbiology, Parasitology and Hygiene (LMPH), Infla-Med Centre of Excellence, University of Antwerp, Universiteitsplein 1, Antwerp 2610, Wilrijk, Belgium.ORCID https://orcid.org/0000-0001-8922-7903 Guy CaljonLaboratory of Microbiology, Parasitology and Hygiene (LMPH), Infla-Med Centre of Excellence, University of Antwerp, Universiteitsplein 1, Antwerp 2610, Wilrijk, Belgium.ORCID https://orcid.org/0000-0002-4870-3202 Jennifer RileyDrug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, DD1 5EH, U.K.
M Cristina NonatoCenter for the Research and Advancement in Fragments and Molecular Targets (CRAFT), School of Pharmaceutical Sciences at Ribeirao Preto, University of São Paulo, Ribeirão Preto 14040-903, SP, Brazil.ORCID https://orcid.org/0000-0002-4916-1505 Flavio S EmeryCenter for the Research and Advancement in Fragments and Molecular Targets (CRAFT), School of Pharmaceutical Sciences at Ribeirao Preto, University of São Paulo, Ribeirão Preto 14040-903, SP, Brazil.ORCID https://orcid.org/0000-0002-8652-7123 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Neglected tropical diseases such as Chagas disease remain poorly served by current chemotherapies due to toxicity and the emergence of drug resistance. Nitroaromatic compounds represent an established antitrypanosomal strategy, relying on bioactivation by
Indexed as
compound fragmentationdrug discoveryneglected tropical diseasesnitrofuranNitroreductasetrypanosomatids
Identifiers
PMID42305192
PMCPMC13266641
What Socratic holds
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