Evidence mapPaperPMID 42305515Full record

ArticleTranslational cancer research2026

Advancing the understanding of tumor microenvironment through medical imaging based on bibliometric analysis.

Keling Huang, Ziqing Han, Yufei Xia, Xinjing Lou, Xinyu Wu, Ruizhi Fu, Linyu Wu, Chen Gao

Abstract read
In one paragraph

Article in Translational cancer research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Keling Huang *Department of Radiology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Ziqing Han *Department of Radiology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Yufei XiaDepartment of Radiology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Xinjing LouDepartment of Radiology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Xinyu WuDepartment of Radiology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Ruizhi FuDepartment of Radiology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Linyu WuDepartment of Radiology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Chen GaoDepartment of Radiology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: As a key diagnostic and monitoring tool, medical imaging has drawn considerable attention in tumor microenvironment (TME) research, emphasizing the need to understand current research trends, key focus areas, and emerging developments. To explore this field comprehensively, this study utilizes bibliometric methods to analyze research on the TME through medical imaging. Methods: The relevant research publications were retrieved from the Web of Science Core Collection (WoSCC) database. CiteSpace was utilized to visualize the co-occurrence of institutions and keywords and create dual-map overlay of journals. VOSviewer generated visual maps for authors, citations, and references. Furthermore, some analyzed data, including publication trends and cooperative relationships, were plotted using R. Results: The final study included 1,256 articles for further analysis. The number of publications rose steadily from 5 in 2008 to 215 in 2025, with citations also showing sustained growth from 4 to 5,628 over the years. The China (n=446, 35.51%) was the most prominent contributor. Krishna Murali C. (n=16) had the highest publication count. The USA (total link strength =201), the University of California System (n=42), and Ellingson Benjamin M. (total link strength =82, collaboration =26) were the respective leaders in the field. Conclusions: This study highlights the current research status and hotspots in TME through medical imaging and points to the feasibility of using medical imaging to evaluate the TME components more accurately. The potential for monitoring the response to immunotherapy and image-guided individualized treatment will be key future research trends.

Indexed as

bibliometric analysismedical imagingneoplasmstumorTumor microenvironment (TME)

Identifiers

PMID42305515
PMCPMC13265181

What Socratic holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.