Evidence map›Paper›PMID 42305862›Full record

ArticleKidney medicine2026

Kidney Function and Mortality in Mexico: Prospective Study of 130,000 Adults.

Diego Aguilar-Ramirez, Roberto Tapia-Conyer, William G Herrington, Raúl Ramirez-Reyes, Adrián Garcilazo-Ávila, Carlos González-Carballo, Rogelio Santacruz-Benitez, Omar Yaxmehen Bello-Chavolla, Fiona Bragg, Louisa Gnatiuc Friedrichs and 15 more

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Article in Kidney medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Diego Aguilar-RamirezClinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Roberto Tapia-ConyerFaculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico.
William G HerringtonClinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Raúl Ramirez-ReyesExperimental Research Unit from the Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico.
Adrián Garcilazo-ÁvilaExperimental Research Unit from the Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico.
Carlos González-CarballoExperimental Research Unit from the Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico.
Rogelio Santacruz-BenitezExperimental Research Unit from the Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico.
Omar Yaxmehen Bello-ChavollaResearch Division, Instituto Nacional de Geriatría, Mexico City, Mexico.
Fiona BraggClinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Louisa Gnatiuc FriedrichsClinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Michael HillClinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Lisa HollandClinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Jason TorresClinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Eirini TrichiaClinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Michael TurnerClinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Natalie StaplinClinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Rachel WadeClinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Doreen ZhuClinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Rory CollinsClinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Richard HaynesClinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Richard PetoClinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Jaime BerumenExperimental Research Unit from the Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico.
Jesus Alegre-DíazExperimental Research Unit from the Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico.
Pablo Kuri-MoralesFaculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico.
Jonathan R EmbersonClinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rationale & Objective: Reduced kidney function is strongly associated with higher mortality, but most evidence is from high-income populations. This study evaluated the relevance of kidney function to cause-specific mortality in Mexico, a country where diabetes is common and chronic kidney disease (CKD) is a major cause of morbidity and mortality. Study Design: Prospective study of Mexican adults aged ≥35 years at recruitment (1998-2004) who were followed until October 2022. Setting & Participants: Participants recruited into the Mexico City Prospective Study. Analyses focused on 126,245 participants aged 35-74 years at recruitment without prior disease (except diabetes or CKD). Exposures: Estimated glomerular filtration rate (eGFR). Outcomes: Cause-specific mortality. Analytical Approach: Cox regression was used to relate eGFR to cause-specific mortality. Analyses were adjusted for sociodemographic and lifestyle factors, anthropometry, and diabetes. Results: Among 40,996 men and 85,249 women aged 35-74 years, median eGFR was 102 (IQR, 91-110) mL/min/1.73 m Limitations: Data on urinary albumin and nonfatal disease outcomes were unavailable. Conclusions: In Mexico, decreased kidney function is strongly associated with premature mortality, mainly from vascular, kidney, and infective causes. Prevention and management of CKD, particularly in individuals with diabetes, should be central to disease-prevention policies.

Indexed as

cause-specific mortalitykidney functionMexicoprospective studyTK

Identifiers

PMID42305862
PMCPMC13265878

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.