Evidence map›Paper›PMID 42306187›Full record

ArticleJournal of hepatocellular carcinoma2026

Development and Validation of a Nomogram Predictive Model for Massive Ascites After Hepatectomy in Patients with Primary Hepatocellular Carcinoma.

Ao Men, Dapeng Sun, Xiuqing Sun, Luyuan Jin, Bailiang Liu, Fengyang Chen, Boyuan Nan, Wenxin Wang, Lei Han, Wei Zhang

Abstract read
In one paragraph

Article in Journal of hepatocellular carcinoma, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ao Men *Department of Hepatobiliary and Thyroid Surgery, General Hospital of Northern Theater Command, Shenyang, Liaoning, People's Republic of China.
Dapeng Sun *Department of Hepatobiliary and Thyroid Surgery, General Hospital of Northern Theater Command, Shenyang, Liaoning, People's Republic of China.
Xiuqing Sun *Department of Hepatobiliary and Thyroid Surgery, General Hospital of Northern Theater Command, Shenyang, Liaoning, People's Republic of China.
Luyuan JinDepartment of Hepatobiliary and Thyroid Surgery, General Hospital of Northern Theater Command, Shenyang, Liaoning, People's Republic of China.
Bailiang LiuDepartment of Hepatobiliary and Thyroid Surgery, General Hospital of Northern Theater Command, Shenyang, Liaoning, People's Republic of China.
Fengyang ChenDepartment of Hepatobiliary and Thyroid Surgery, General Hospital of Northern Theater Command, Shenyang, Liaoning, People's Republic of China.
Boyuan NanDepartment of Hepatobiliary and Thyroid Surgery, General Hospital of Northern Theater Command, Shenyang, Liaoning, People's Republic of China.ORCID 0000-0001-6467-4811
Wenxin WangDepartment of Hepatobiliary and Thyroid Surgery, General Hospital of Northern Theater Command, Shenyang, Liaoning, People's Republic of China.
Lei HanDepartment of Hepatobiliary and Thyroid Surgery, General Hospital of Northern Theater Command, Shenyang, Liaoning, People's Republic of China.
Wei ZhangDepartment of Hepatobiliary and Thyroid Surgery, General Hospital of Northern Theater Command, Shenyang, Liaoning, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To develop and validate a nomogram for predicting massive ascites after hepatectomy in hepatocellular carcinoma (HCC) patients. Methods: A retrospective, single‑center study of 232 HCC patients who underwent hepatectomy (February 2021 - July 2025) was conducted. Patients with preoperative bile leakage or active hemorrhage were excluded. Patients were grouped by postoperative ascites status (massive, n=66; non-massive, n=166). Predictors were screened via univariate and multivariate logistic regression. A nomogram was built and internally validated using 1000 bootstrap samples. Performance was assessed via ROC analysis, calibration, and decision curve analysis (DCA), Clinical Impact Curve (CIC. Results: Multivariate analysis identified four independent predictors: platelet count (OR=0.985), AST (OR=1.027), portal hypertension (OR=5.288), and operative time (OR=5.011). The nomogram achieved an AUC of 0.837 (95% CI: 0.781-0.892) with good calibration (H-L test, P=0.860). DCA showed clinical net benefit across thresholds [0.00-0.71] and [0.86-0.93]and the clinical impact curve showing good concordance at risk thresholds above 0.4. Conclusion: The nomogram accurately predicts massive ascites risk using four perioperative variables and demonstrates strong clinical utility for individualized management.

Indexed as

asciteshepatectomyhepatocellular carcinomanomogrampostoperative complications

Identifiers

PMID42306187
PMCPMC13267821

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.