Evidence map›Paper›PMID 42306191›Full record

ArticleCurrent research in food science2026

L-Theanine ameliorates high-protein diet-associated hepatic glucose and lipid metabolic alterations by promoting fatty acid β-oxidation and suppressing lipid synthesis and gluconeogenesis in rats.

Sha Liu, Lanlan Li, Kai Yao, Lin He, Yong Yuan, Yueping Tan, Feiyan Yin, Zhihua Gong, Wenjun Xiao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current research in food science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sha LiuKey Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha, Hunan, 410128, China.
Lanlan LiKey Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha, Hunan, 410128, China.
Kai YaoKey Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha, Hunan, 410128, China.
Lin HeKey Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha, Hunan, 410128, China.
Yong YuanHunan Tea Group Co., Ltd., Changsha, Hunan, 410126, China.
Yueping TanHunan Tea Group Co., Ltd., Changsha, Hunan, 410126, China.
Feiyan YinHunan Tea Group Co., Ltd., Changsha, Hunan, 410126, China.
Zhihua GongKey Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha, Hunan, 410128, China.
Wenjun XiaoKey Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha, Hunan, 410128, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-protein diets (HPDs) have the potential to reduce body weight, yet excessive protein intake can induce hepatic metabolic dysregulation and insulin resistance. L-theanine (LTA), a unique amino acid abundantly present in tea leaves, regulates protein metabolism under HPD conditions. However, its influence on glucose and lipid metabolism remains unclear. In this study, Sprague-Dawley rats were fed either a standard maintenance diet (20% of energy from protein) or HPDs containing 30%, 40%, or 50% of energy from protein, and were administered LTA at different doses (0, 100, 200, or 400 mg kg

Indexed as

Fatty acid β-oxidationGluconeogenesisHigh-protein dietLipid synthesisLiver metabolismL-theanine

Identifiers

PMID42306191
PMCPMC13266236

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.