Evidence map›Paper›PMID 42306554›Full record

ArticleJBMR plus2026

Transcriptional profiling of otic capsule and femur in the oim mouse model of osteogenesis imperfecta.

Ugur M Ayturk, Miracle Rogers, Ketsia Seide, David Oliver, Yurii Chinenov, Ezgi Aydin, Erin M Carter, Cathleen L Raggio

Abstract read
In one paragraph

Article in JBMR plus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ugur M AyturkInstitute for Biological Sciences, Hospital for Special Surgery, New York NY 10021, United States.ORCID https://orcid.org/0000-0001-6625-2743
Miracle RogersInstitute for Biological Sciences, Hospital for Special Surgery, New York NY 10021, United States.
Ketsia SeideInstitute for Biological Sciences, Hospital for Special Surgery, New York NY 10021, United States.
David OliverInstitute for Biological Sciences, Hospital for Special Surgery, New York NY 10021, United States.
Yurii ChinenovInstitute for Biological Sciences, Hospital for Special Surgery, New York NY 10021, United States.
Ezgi AydinInstitute for Biological Sciences, Hospital for Special Surgery, New York NY 10021, United States.
Erin M CarterInstitute for Biological Sciences, Hospital for Special Surgery, New York NY 10021, United States.ORCID https://orcid.org/0009-0007-8754-6354
Cathleen L RaggioInstitute for Biological Sciences, Hospital for Special Surgery, New York NY 10021, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hearing loss is a common and debilitating complication of the brittle bone disorder osteogenesis imperfecta (OI). Existing treatments that are designed to address age-related hearing loss in the broader population do not meet the needs of OI patients, who exhibit skeletal fragility and begin to lose their hearing when they are young-adults. The biologic mechanisms responsible for hearing loss in OI are unknown, hindering the development of preventative therapies. To identify potential mechanisms that drive this condition, we performed transcriptome profiling on femoral and otic capsule specimens obtained from the

Indexed as

bonehearing lossmouse modelosteogenesis imperfectaRNA-sequencing

Identifiers

PMID42306554
PMCPMC13267895

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.