Evidence map›Paper›PMID 42307139›Full record

ReviewApplied and environmental microbiology2026

Polymer- and peptide-based antiviral surface coatings: progress, mechanistic gaps, and future directions.

Umme Laila Urmi, Mark D P Willcox

Abstract readReview
In one paragraph

Review in Applied and environmental microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Umme Laila UrmiSchool of Optometry and Vision Science, University of New South Wales, Sydney, NSW, Australia.ORCID 0000-0003-1327-1638
Mark D P WillcoxSchool of Optometry and Vision Science, University of New South Wales, Sydney, NSW, Australia.ORCID 0000-0003-3842-7563

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Indirect transmission of viruses via contaminated surfaces highlights the need for effective antiviral coatings. Recent advances have led to the development of diverse surface engineering strategies, including organic (polymer- and peptide-based) and inorganic (metal-based) coatings. While polymer and peptide-based systems have been extensively explored in the antibacterial field, their application in antiviral coatings remains underexplored despite their demonstrated ability to reduce viral titers. This minireview provides a mechanistically informed overview of polymer- and peptide-based antiviral surface coatings. We summarize recent studies with a focus on coating materials, methods, physicochemical characterization techniques, target viruses, and antiviral performance. In addition, we critically evaluate key limitations in the field, including the lack of standardized testing protocols, restricted diversity of surfaces and viruses, and insufficient assessment of coating durability and cytotoxicity. Finally, we discuss future directions focused on standardized and rationally designed evaluation frameworks to support the practical translation of antiviral coatings.

Indexed as

Antiviral AgentsPeptidesPolymersVirusesSurface PropertiesAntiviral AgentsPeptidesPolymersantiviral surface coatingpeptide-based coatingspolymer-based coatingsurface-mediated virus transmission

Identifiers

PMID42307139
PMCPMC13390490

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.