ReviewmBio2026
Interferon-induced transmembrane proteins in cancer and virus biology: a membrane perspective.
Review in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The interferon-induced transmembrane proteins (IFITMs) are a family of potent broad-spectrum antiviral factors that restrict enveloped viruses primarily by altering the biophysical properties of membranes, thereby preventing viral-cellular fusion. While their antiviral mechanisms are well established, increasing evidence suggests that IFITMs can also play important roles in cancer biology by remodeling of the cancer cell surface proteome and by modulating signaling pathways involved in proliferation, cell survival, and metastasis. In this review, we summarize the diverse biological functions attributed to IFITMs over the years; we highlight the salient aspects of their biology; and we propose a unifying conceptual framework in which seemingly diverse functions of IFITMs in virology and cancer biology can be understood through their capacity to regulate the behavior of membranes.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.