In one paragraphArticle in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
22 authors.
Kateryna MurlanovaDepartment of Physiology and Biophysics, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA.ORCID 0000-0001-9236-6648 Ksenia Novototskaya-VlasovaDepartment of Physiology and Biophysics, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA.
Shovgi HuseynovDepartment of Physiology and Biophysics, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA.ORCID 0000-0002-3663-7236 Olga PletnikovaDepartment of Pathology and Anatomical Sciences, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA.ORCID 0000-0001-6516-4944 Rebecca D HowellDepartment of Pharmacology and Toxicology, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA.
Yan JouroukhinDepartment of Physiology and Biophysics, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA.ORCID 0000-0002-5308-1276 Dong Won KimDanish Research Institute of Translational Neuroscience (DANDRITE), Nordic EMBL Partnership for Molecular Medicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0001-8624-0168 Adrian Eddy-Sulaiman JensonDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0002-1900-3231 Juhyun LeeEmotion, Cognition & Behavior Research Group, Korea Brain Research Institute, Daegu, Republic of Korea.
Cheng QinDepartment of Physiology and Biophysics, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA.
Stephen R ThompsonDepartment of Physiology and Biophysics, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA.
Vikyath SarafDepartment of Pharmacology and Toxicology, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA.
Michael J MoralesDepartment of Physiology and Biophysics, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA.ORCID 0000-0002-6528-4927 Eduardo Cortes GomezDepartment of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.ORCID 0000-0002-0966-6488 Russell L MargolisDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0003-3024-8595 Frederick C NuciforaDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0009-0003-1054-0342 Spencer R RosarioDepartment of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.ORCID 0000-0002-2626-9257 Andrew A PieperDepartment of Psychiatry, Department of Neurosciences, Department of Pathology, Case Western Reserve University and Institute for Transformative Molecular Medicine, Cleveland, OH, USA.ORCID 0000-0001-6299-6577 Henry G WithersDepartment of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.ORCID 0000-0002-9746-9352 Samir Haj-DahmaneDepartment of Pharmacology and Toxicology, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA.
Juhyun KimDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0002-3098-5010 Mikhail V PletnikovDepartment of Physiology and Biophysics, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA.ORCID 0000-0002-5584-2577 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
The basic helix-loop-helix transcription factor neuronal PAS (Per, Arnt, Sim) domain protein 3 (NPAS3) provides transcriptional regulation of metabolic pathways and is highly expressed in astrocytes. NPAS3 variants have been associated with cognitive dysfunction under several neuropsychiatric conditions, but the underlying brain cell type-specific mechanisms remain obscure. Here, we report that NPAS3 is a key regulator of mitochondrial bioenergetics in astrocytes in the mouse brain. Selective deletion of
Indexed as
AstrocytesBasic Helix-Loop-Helix ProteinsCognitionEnergy MetabolismMitochondriaNerve Tissue ProteinsAnimalsMiceMice, KnockoutOxidative PhosphorylationPrefrontal CortexPyramidal CellsSynaptic TransmissionBasic Helix-Loop-Helix ProteinsNerve Tissue Proteins
Identifiers
PMID42308317
PMCPMC13274620
What Socratic holds
Textmetadata
LicenceCC BY
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