Evidence map›Paper›PMID 42310470›Full record

ReviewNature reviews. Gastroenterology & hepatology2026

Synthetic data generation: challenges and perspectives for gastrointestinal medicine.

Panagiota Gatoula, Dimitris K Iakovidis, Dimitrios E Diamantis, Vajira Thambawita, Thomas de Lange, Anastasios Koulaouzidis

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Gastroenterology & hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Panagiota GatoulaDepartment of Computer Science and Biomedical Informatics, University of Thessaly, Lamia, Greece.
Dimitris K IakovidisDepartment of Computer Science and Biomedical Informatics, University of Thessaly, Lamia, Greece.ORCID http://orcid.org/0000-0002-5027-5323
Dimitrios E DiamantisDepartment of Computer Science and Biomedical Informatics, University of Thessaly, Lamia, Greece.
Vajira ThambawitaDepartment of Holistic Systems, SimulaMet, Oslo, Norway.ORCID http://orcid.org/0000-0001-6026-0929
Thomas de LangeDepartment of Medicine, Geriatrics and Emergency Care - Mölndal, Sahlgrenska University Hospital, Gothenburg, Sweden.ORCID http://orcid.org/0000-0003-3989-7487
Anastasios KoulaouzidisDepartment of Clinical Research, University of Southern Denmark, Odense, Denmark. akoulaouzidis@hotmail.com.ORCID http://orcid.org/0000-0002-2248-489X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the era of artificial intelligence, machines are demonstrating an unprecedented capacity to learn from massive amounts of real-world data to perform human-like cognitive processes, enabling them to recognize environments, objects, and conditions and make critical decisions more accurately than ever. In the medical field, the potential to generate realistic, privacy-preserving, unbiased synthetic data can be the key to unlocking the potential of artificial intelligence in medicine and overcoming the current barriers such as data privacy concerns and high data curation costs. Advanced data-driven solutions could lead towards more robust clinical decision support systems and enhanced clinical training. This Perspective critically examines current and emerging advances in synthetic data generation, and highlights its anticipated transformational effect for early and efficient prevention, diagnosis and treatment of gastrointestinal diseases. Research challenges and directions are identified for leveraging the benefits of synthetic data as well as translating and adopting them in clinical workflows.

Indexed as

Artificial IntelligenceGastroenterologyGastrointestinal DiseasesDecision Support Systems, ClinicalHumans

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.