Evidence map›Paper›PMID 42311737›Full record

ArticleCureus2026

Sacral Neuromodulation Outcomes for Managing Urinary Incontinence in Patients With Overactive and Neurogenic Bladder.

Chelsae Nugent, Gabriel Carreño Galeano, Kellen Choi

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chelsae NugentDepartment of Urology, University of Louisville School of Medicine, Louisville, USA.
Gabriel Carreño GaleanoDepartment of Urology, University of Louisville Hospital, Louisville, USA.
Kellen ChoiDepartment of Urology, University of Louisville Hospital, Louisville, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective This study aimed to assess urinary outcomes after sacral neuromodulation (SMN) implantation in patients with neurogenic bladder (NGB) and overactive bladder (OAB). Methods We conducted a retrospective chart review of patients who underwent permanent SNM implantation by a single surgeon between 2018 and 2025. Associated clinical encounters, operative reports, and patient-reported outcome measures were reviewed. Statistical analyses were performed using R (R Foundation for Statistical Computing, Vienna, Austria). Continuous variables were summarized using medians and interquartile ranges (IQR) and categorical variables using counts and percentages. Between-group comparisons were assessed using the Wilcoxon rank-sum test and chi-squared or Fisher's exact tests. Within-patient pre- and post-implant comparisons were analyzed using the Wilcoxon signed-rank test. Statistical significance was defined as p<0.05. Results One hundred and sixty-two patients who underwent permanent SNM implantation were included (NGB n=50; OAB n=112). The NGB group was younger (median age: 44.5 years; p<0.001) and had a slightly lower body mass index (BMI) (p=0.046). The OAB group was older (median age: 61.5 years) with BMI >30 and a varied sex distribution (p<0.001). Presenting symptoms differed between groups (p<0.001), with incomplete bladder emptying predominating among NGB patients and storage symptoms consistent with OAB predominating in the OAB cohort. Pre- and post-SNM comparisons indicated a decline in frequency, daytime void (p<0.001; r=0.76) and nighttime void (p<0.001; r=0.89), incontinence episodes (p<0.001; r=0.93), and daily pad usage (p<0.001; r=0.90). Despite differences in baseline characteristics and presentation, post-implant urinary outcomes were comparable in NGB patients and OAB patients (p=0.2435). Conclusion SNM implantation led to significant improvement in urinary symptoms in both groups. Post-implant urinary outcomes were comparable between groups despite differences in presentation. These findings suggest SNM effectiveness is better demonstrated by post-implant outcomes rather than by diagnostic category alone and support SNM as a therapeutic option across diverse bladder dysfunction etiologies.

Indexed as

incomplete bladder emptyingneurogenic bladderoveractive bladdersacral neuromodulationurinary incontinence (ui)

Identifiers

PMID42311737
PMCPMC13271769

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.