ArticleSurgical case reports2026
Reversal of Obesity-Related Spinal Epidural Lipomatosis after Metabolic and Bariatric Surgery: A Case Suggesting the Role of Ectopic Fat Reduction.
Article in Surgical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionSpinal epidural lipomatosis (SEL) is a disorder characterized by excessive accumulation of epidural adipose tissue, resulting in spinal canal stenosis and neurological symptoms. In recent years, obesity-related SEL has been increasingly recognized as a manifestation of ectopic fat deposition associated with metabolic dysfunction and has been re-evaluated as a potentially reversible condition following weight reduction. However, reports describing radiological and clinical improvement of SEL after metabolic and bariatric surgery (MBS) remain limited, and this disease concept and therapeutic strategy have not yet gained sufficient attention in Japan. Herein, we report a case of SEL that improved following MBS. CASE PRESENTATION: A 49-year-old man with severe obesity (body weight 160 kg; BMI 48.3 kg/m
conclusionsMBS led to meaningful improvement in patient-oriented outcomes accompanied by radiological resolution of SEL. Obesity-related SEL may represent a reversible condition driven by ectopic fat accumulation, and MBS may serve as a therapeutic option in carefully selected patients.
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