Evidence map›Paper›PMID 42311876›Full record

ArticleERJ open research2026

Characteristics and management of asthma from the China Asthma Data Registry Project.

Kefang Lai, Tingting Xu, Ping Chen, Jiangtao Lin, Chuntao Liu, Changzheng Wang, Xin Zhou, Jianping Zhao, Huahao Shen, Mingjuan Zhou and 21 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ERJ open research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Kefang LaiState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.
Tingting XuState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.
Ping ChenDepartment of Respiratory, Chinese PLA General Hospital of Northern Theater Command, Shenyang, China.
Jiangtao LinChina-Japan Friendship Hospital, Beijing, China.
Chuntao LiuWest China Hospital of Sichuan University, Chengdu, China.
Changzheng WangXinqiao Hospital, Army Military Medical University, Chongqing, China.
Xin ZhouShanghai general hospital, Shanghai, China.
Jianping ZhaoDepartment of Respiratory Medicine, Tongji Hospital, Tongji Medical College, Hua Zhong University of Science and Technology, Wuhan, China.
Huahao ShenDepartment of Respiratory and Critical Care Medicine, Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China.
Mingjuan ZhouGuangdong Provincial Hospital of Chinese Medicine, Guangzhou, China.
Jianyong ZhangThe Second Department of Pulmonary and Critical Care Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Xiuqing LiaoDepartment of Respiratory Medicine, Chongqing University Fuling Hospital, Chongqing, China.
Xiujuan GengBenxi Central Hospital, Benxi, China.ORCID https://orcid.org/0009-0002-0244-1080
Feng WuDepartment of Pulmonary and Critical Care Medicine, Huizhou Third People's Hospital, Guangzhou Medical University, Huizhou, China.
Baoan GaoYichang Central People's Hospital, Yichang, China.
Chen QiuShenzhen People's Hospital, Shenzhen, China.
Yunhui ZhangThe First People's Hospital of Yunnan Province, Kunming, China.
Meiling JinDepartment of Pulmonary Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Xianwei YeDepartment of Pulmonary and Critical Care Medicine, Guizhou Provincial People's Hospital, Guiyang, China.
Liping ChenThe Second Affiliated Hospital of Shenyang Medical College, Shenyang, China.
Qiaojie HeDepartment of Allergy, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.
Xinming SuDepartment of Respiratory and Critical Care Medicine, the First Affiliated Hospital of China Medical University, Shenyang, China.
Xianming FanDepartment of Respiratory and Critical Care Medicine, The Affiliated Hospital, Southwest Medical University, Luzhou, China.
Guochao ShiRuijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Chong BaiChanghai Hospital of Shanghai, Shanghai, China.
Guangfa WangPeking University First Hospital, Beijing, China.
Fang YiState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.
Mei JiangState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.ORCID https://orcid.org/0000-0002-7393-2664
Rongchang ChenState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.
Kian Fan ChungNational Heart and Lung Institute, Imperial College London, Royal Brompton and Harefield Hospital, London, UK.ORCID https://orcid.org/0000-0001-7101-1426
Nanshan ZhongState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There is limited information available on patients with asthma in hospitals in China. We investigated their clinical and phenotypic characteristics and management. Methods: The China Asthma Data Registry Project (CHART) study is a multicentre, hospital-based, prospective, observational study in which patients were recruited from outpatient clinics. This analysis used baseline cross-sectional data from patients with asthma (≥12 years) enrolled at 58 tertiary hospitals in China between 25 March 2018 and 11 July 2019. Results: A total of 20 683 patients with asthma (56.2% female, 15.0% patients with active tobacco use) were enrolled. Overall, 22.8% had uncontrolled asthma, 39.5% had partially controlled asthma. Furthermore, 45.3% experienced ≥1 exacerbation annually, including 31.7% who required hospitalisation, with only 21.4% having previously used inhaled corticosteroids (ICSs) in the past year. Cough (80.0%) was the most common symptom, followed by wheezing (70.7%), with 14.6% having cough-predominant asthma and 11.4% having cough-variant asthma. Multivariate logistic regression revealed that cough severity independently predicted poor control, irrespective of airflow limitation or inflammatory status. The association was stronger in ICS users than in nonusers across all cough severity metrics: a visual analogue scale (VAS) score ≥40 (aOR 3.88-5.47 Conclusions: We found significant suboptimal control, a high prevalence of cough-related phenotypes, frequent exacerbations and hospital admissions in patients with asthma attending hospitals. This underscores the need to prioritise the assessment and treatment of cough in asthma.

Identifiers

PMID42311876
PMCPMC13266435

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.