Evidence map›Paper›PMID 42311889›Full record

ArticleFrontiers in medicine2026

Predictive value of initial triage vital signs for in-hospital mortality in acute aortic dissection patients: a retrospective study in the emergency department.

Nan Xie, Yixiao Shi

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Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Nan Xie *Emergency Department of West China Hospital, West China School of Nursing, Sichuan University, Chengdu, China.
Yixiao Shi *Operating Room of Anesthesia Surgery Center, West China Hospital/West China School of Nursing, Sichuan University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acute aortic dissection (AAD) is a life-threatening emergency requiring rapid diagnosis and treatment. Vital signs obtained at triage are immediately available and may provide useful information for early risk stratification. Objectives: To evaluate whether triage vital signs are independently associated with in-hospital mortality in patients with AAD, with a specific focus on analyzing heart rate as a categorical variable and blood pressure in clinically relevant units. Methods: We performed a retrospective cohort study of 702 consecutive patients with AAD admitted to the emergency department of a tertiary hospital in China between January 1 and November 23, 2024. Heart rate was categorized as bradycardia (<60 bpm), normal (60-100 bpm), or tachycardia (>100 bpm). Blood pressure was analyzed per 10-mmHg change. Variables significant in univariate analysis ( Results: Among 702 patients, 293 (41.7%) died during hospitalization. Multivariate logistic regression identified older age (adjusted OR 1.029 per year, 95% CI 1.017-1.041), male sex (adjusted OR 1.495, 95% CI 1.036-2.157), bradycardia (adjusted OR 2.500, 95% CI 1.300-4.800), tachycardia (adjusted OR 1.800, 95% CI 1.100-2.900), lower body temperature (adjusted OR 1.499 per 1 °C decrease, 95% CI 1.082-2.075), and higher diastolic blood pressure (adjusted OR 1.105 per 10-mmHg increase, 95% CI 1.001-1.220) as independent risk factors for in-hospital mortality. The model demonstrated acceptable discrimination (mean cross-validated AUC 0.71, 95% CI 0.68-0.74). Conclusion: Initial triage vital signs, particularly deviations in heart rate (both low and high), lower body temperature, and higher diastolic blood pressure, are independent predictors of in-hospital mortality in patients with AAD. Assessing these readily available parameters can support early risk stratification in the emergency department.

Indexed as

acute aortic dissectionemergency departmentin-hospital mortalitytriagevital signs

Identifiers

PMID42311889
PMCPMC13268940

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