Evidence mapPaperPMID 42312767Full record

ReviewJACC. Advances2026

Cardiometabolic Health in Pregnancy: Prevention, Management, and Long-Term Implications.

Colleen M Harrington, Amy Sarma, Amanda Jowell, Jessica Passarelli, Camille Powe, Natalie A Bello, Jennifer Lewey, Melinda B Davis, Lily Nedda Dastmalchi, Garima Sharma and 2 more

Abstract readReview
In one paragraph

Review in JACC. Advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Colleen M HarringtonMass General Brigham Heart Vascular Institute, Women's Heart Health Program, Boston, Massachusetts, USA. Electronic address: charrington12@mgh.harvard.edu.
Amy SarmaMass General Brigham Heart Vascular Institute, Women's Heart Health Program, Boston, Massachusetts, USA.
Amanda JowellDepartment of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
Jessica PassarelliMass General Brigham Heart Vascular Institute, Women's Heart Health Program, Boston, Massachusetts, USA.
Camille PoweDepartment of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
Natalie A BelloDepartment of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA; Atria Health and Research Institute, New York, New York, USA.
Jennifer LeweyDivision of Cardiovascular Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Melinda B DavisDivision of Cardiology, University of Michigan, Ann Arbor, Michigan, USA.
Lily Nedda DastmalchiDivision of Cardiology, Inova Schar Heart and Vascular, Falls Church, Virginia, USA.
Garima SharmaDivision of Cardiology, Inova Schar Heart and Vascular, Falls Church, Virginia, USA.
Michael HonigbergMass General Brigham Heart Vascular Institute, Women's Heart Health Program, Boston, Massachusetts, USA.
Nandita ScottMass General Brigham Heart Vascular Institute, Women's Heart Health Program, Boston, Massachusetts, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiometabolic health across the reproductive lifespan is a critical determinant of short-term pregnancy outcomes and long-term cardiovascular risk for both mother and offspring. Pregnancy serves as a unique physiological stress test and a key opportunity for primordial and primary prevention. Cardiometabolic risk factors-including hypertension, dyslipidemia, obesity, and hyperglycemia-are strongly associated with adverse pregnancy outcomes, such as hypertensive disorders of pregnancy and gestational diabetes, which confer substantial lifelong cardiovascular risk. This review provides a clinically actionable framework for optimizing cardiometabolic health before, during, and after pregnancy. We highlight evidence-based strategies for risk factor modification, including blood pressure control, glycemic management, lipid optimization, nutrition, physical activity, sleep health, and substance cessation, while addressing physiologic adaptations, therapeutic limitations, and care fragmentation. Emphasis is placed on multidisciplinary, life-course approaches and integration of emerging care models. Bridging gaps across preconception, pregnancy, and postpartum care is essential to improving maternal outcomes and long-term cardiovascular health.

Indexed as

adverse pregnancy outcomescardiometabolic healthcardio-Obstetricspregnancypreventive cardiologyrisk reduction

Identifiers

PMID42312767
PMCPMC13309322

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.