ArticleJACC. Case reports2026
Excimer Laser for Calcified Nodule-Driven Early Stent Failure: Peristent Calcium Modification.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- ELCA for In-Stent Calcified Nodules: Mechanistic Rationale in the Absence of Evidence.JACC. Case reports · 2026Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn-stent restenosis (ISR) in hemodialysis patients is frequently driven by calcified nodules. The role of excimer laser coronary atherectomy (ELCA) in disrupting peristent calcification remains under-recognized. CASE SUMMARY: An 81-year-old man on hemodialysis underwent primary percutaneous coronary intervention for ST-segment elevation myocardial infarction involving the ostial right coronary artery. Three months later, angiography revealed subocclusive ISR. Intravascular ultrasound demonstrated a protruding calcified plaque flap suggestive of calcified nodule reprotrusion. ELCA using a 1.4-mm catheter resulted in fragmentation of the protruding calcified tissue and disruption of peristent calcium. DISCUSSION: Despite transient contrast staining, 6-month angiography and optical coherence tomography demonstrated durable patency and stable tissue healing.
conclusionELCA may be an effective adjunctive strategy for structurally driven ISR caused by calcified nodule reprotrusion. TAKE-HOME MESSAGES: Early ISR in hemodialysis patients may be structurally driven by recurrent calcified nodule protrusion through the stent struts rather than neointimal proliferation. ELCA can facilitate luminal gain through fragmentation of protruding calcified nodules and photomechanical disruption of peristent calcium.
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Registered trials
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