Evidence map›Paper›PMID 42313158›Full record

ArticleAntimicrobial agents and chemotherapy2026

Improved protocols using sodium artesunate for the treatment of experimental cerebral malaria.

Melina Pedroso Merlone, Fabiana Gomes, Guilherme Salgado Sanches, Cláudio Tadeu Daniel-Ribeiro, Leonardo José de Moura Carvalho

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Melina Pedroso MerloneLaboratório de Pesquisa em Malária, Fundação Oswaldo Cruz (Fiocruz), Instituto Oswaldo Cruz, Rio de Janeiro, Brazil.ORCID 0009-0009-9431-1590
Fabiana GomesLaboratório de Pesquisa em Malária, Fundação Oswaldo Cruz (Fiocruz), Instituto Oswaldo Cruz, Rio de Janeiro, Brazil.
Guilherme Salgado SanchesLaboratório de Pesquisa em Malária, Fundação Oswaldo Cruz (Fiocruz), Instituto Oswaldo Cruz, Rio de Janeiro, Brazil.
Cláudio Tadeu Daniel-RibeiroLaboratório de Pesquisa em Malária, Fundação Oswaldo Cruz (Fiocruz), Instituto Oswaldo Cruz, Rio de Janeiro, Brazil.
Leonardo José de Moura CarvalhoLaboratório de Pesquisa em Malária, Fundação Oswaldo Cruz (Fiocruz), Instituto Oswaldo Cruz, Rio de Janeiro, Brazil.ORCID 0000-0003-0133-6430

Funding

Brazilian National Council for Scientific and Technological Development-CNPq 140791/2022-1Brazilian National Council for Scientific and Technological Development-CNPq 164367/2021-7Brazilian National Council for Scientific and Technological Development-CNPq 307891/2025-9Brazilian National Council for Scientific and Technological Development-CNPq 310445/2017-5Brazilian National Council for Scientific and Technological Development-CNPq 316462/2021-7National Institute of Science and Technology in Neuroimmunomodulation 408201/2024-0Rio de Janeiro research funding agency E-26/200.314/2025Rio de Janeiro research funding agency E-26/200.491/2025Rio de Janeiro research funding agency E-26/200.492/2025Rio de Janeiro research funding agency E-26/202.921/2018
6 · The paper itself

Abstract

Artemether and artesunate are effective antimalarial drugs in rescue therapies of

Indexed as

AntimalarialsArtemisininsMalaria, CerebralAnimalsArtesunateDisease Models, AnimalFemaleMiceParasitemiaPlasmodium bergheiAntimalarialsArtemisininsArtesunateartesunatecerebral malariatherapeutics

Identifiers

PMID42313158
PMCPMC13436405

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.