Evidence map›Paper›PMID 42313336›Full record

ArticleInternational journal of clinical pharmacy2026

Evidence on interventions that target prescribing appropriateness in older adults attending the emergency department and other acute care settings: a scoping review.

Lauren Fernandes, Daniel McCarthy, Claire McCormack, Aoife Leahy, Anne Harnett, Abdirahman Mohamed, Ahmed Gabr, Margaret O'Connor, Rose Galvin

Abstract readScoping Review
In one paragraph

Article in International journal of clinical pharmacy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lauren FernandesSchool of Allied Health, Faculty of Education and Health Sciences, University of Limerick, Limerick, Ireland. lauren.fernandes@ul.ie.
Daniel McCarthySchool of Medicine, Faculty of Education and Health Sciences, University of Limerick, Limerick, Ireland.
Claire McCormackSchool of Medicine, Faculty of Education and Health Sciences, University of Limerick, Limerick, Ireland.
Aoife LeahySchool of Allied Health, Faculty of Education and Health Sciences, University of Limerick, Limerick, Ireland.
Anne HarnettSchool of Medicine, Faculty of Education and Health Sciences, University of Limerick, Limerick, Ireland.
Abdirahman MohamedSchool of Allied Health, Faculty of Education and Health Sciences, University of Limerick, Limerick, Ireland.
Ahmed GabrUniversity Hospital Limerick, Limerick, Ireland.
Margaret O'ConnorSchool of Allied Health, Faculty of Education and Health Sciences, University of Limerick, Limerick, Ireland.
Rose GalvinSchool of Allied Health, Faculty of Education and Health Sciences, University of Limerick, Limerick, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPotentially inappropriate prescribing (PIP) has been associated with various adverse clinical outcomes, particularly in the context of ageing, multimorbidity and polypharmacy. Despite growing interest in front door frailty initiatives in the emergency department (ED) and acute geriatric units (AGUs), no review has focused specifically on interventions targeting PIP, as defined by validated criteria, across both ED and AGU settings.

aimThis scoping review aimed to map the evidence on interventions addressing PIP in older adults attending EDs or AGUs, identify evidence gaps and highlight areas for future research.

methodThis scoping review was conducted in accordance with Joanna Briggs Institute (JBI) methodology and reported using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) Checklist. Medline, Embase, CINAHL Ultimate, Web of Science, Cochrane CENTRAL and grey literature sources were searched from 1991 to 2025 for studies evaluating interventions targeting PIP, defined using validated criteria, in adults aged ≥ 65 years attending the ED or AGUs.

resultsOur search returned 8643 results. Twenty-one studies were identified for inclusion, four of which were randomised controlled trials. The 18 interventions identified encompassed pharmacist-led medication reviews, clinical decision support systems (CDSS), educational/academic detailing programmes or combined approaches. While PIP was frequently a primary outcome measure, few studies reported clinical outcomes or explored prescriber adherence and experiences of older adults and prescribers.

conclusionPharmacist-led medication reviews, CDSS and educational/academic detailing were the main intervention approaches identified. Evidence was heterogeneous and focused mainly on prescribing-related outcomes, with limited assessment of clinical outcomes, prescriber adherence, communication pathways and stakeholder feedback. Future studies should incorporate longer-term follow-up and evaluate patient-centred and implementation outcomes.

Indexed as

Emergency Service, HospitalInappropriate PrescribingAgedHumansPharmacistsRandomized Controlled Trials as TopicAcute geriatric unitAgedEmergency serviceHospitalMedication reviewPharmacistsPotentially inappropriate medication list

Identifiers

PMID42313336
PMCPMC13569505

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.