ReviewEMBO reports2026
Organelle interplay in host responses and mycobacterial resilience.
Review in EMBO reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Mycobacteria exploit host organelles to survive and proliferate within the intracellular environment. In parallel, host cells rely on these organelles to ensure essential biological functions and mount effective immune defenses against invading pathogens. The dynamic competition between host and mycobacteria for control of these organelles represents a central battleground in infection biology and is of increasing scientific interest. Important organelles such as mitochondria, the endoplasmic reticulum, and the Golgi apparatus play pivotal roles in determining the outcome of infection and can tip the balance between pathogen clearance and intracellular survival. Beyond their classical functions in energy production, calcium homeostasis, and protein trafficking, these structures actively participate in immune signaling, metabolism reprogramming, and inflammatory responses. Consequently, they function as powerful defenders against pathogens and, under certain conditions, represent unintentional allies. This review categorizes organelle contributions into two major areas: host-driven cellular defense mechanisms and pathogen-mediated subversion strategies. Recent work in the field is discussed, providing new insights into host-pathogen dynamics and identifying potential therapeutic targets for improved control of mycobacterial infections.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.