Evidence map›Paper›PMID 42315716›Full record

ArticleGeroScience2026

High-resolution MRI evidence for age- and sex-related changes in hippocampal subfield volume during healthy aging.

Megan C Hall, Giorgia Picci, Maggie P Rempe, Jason A John, Lauren K Webert, Kellen M McDonald, Hannah J Okelberry, Hallie J Johnson, Lucy K Horne, Madelyn P Willett and 9 more

Abstract read
PubMed Publisher
In one paragraph

Article in GeroScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Megan C HallInstitute for Human Neuroscience, Boys Town National Research Hospital, Omaha, NE, USA.
Giorgia PicciInstitute for Human Neuroscience, Boys Town National Research Hospital, Omaha, NE, USA.
Maggie P RempeInstitute for Human Neuroscience, Boys Town National Research Hospital, Omaha, NE, USA.
Jason A JohnInstitute for Human Neuroscience, Boys Town National Research Hospital, Omaha, NE, USA.
Lauren K WebertInstitute for Human Neuroscience, Boys Town National Research Hospital, Omaha, NE, USA.
Kellen M McDonaldInstitute for Human Neuroscience, Boys Town National Research Hospital, Omaha, NE, USA.
Hannah J OkelberryInstitute for Human Neuroscience, Boys Town National Research Hospital, Omaha, NE, USA.
Hallie J JohnsonInstitute for Human Neuroscience, Boys Town National Research Hospital, Omaha, NE, USA.
Lucy K HorneInstitute for Human Neuroscience, Boys Town National Research Hospital, Omaha, NE, USA.
Madelyn P WillettInstitute for Human Neuroscience, Boys Town National Research Hospital, Omaha, NE, USA.
Ryan J GlesingerInstitute for Human Neuroscience, Boys Town National Research Hospital, Omaha, NE, USA.
Danielle L RiceInstitute for Human Neuroscience, Boys Town National Research Hospital, Omaha, NE, USA.
Anna T CoutantInstitute for Human Neuroscience, Boys Town National Research Hospital, Omaha, NE, USA.
Kennedy A KressInstitute for Human Neuroscience, Boys Town National Research Hospital, Omaha, NE, USA.
Grant M GarrisonInstitute for Human Neuroscience, Boys Town National Research Hospital, Omaha, NE, USA.
Seth BashfordInstitute for Human Neuroscience, Boys Town National Research Hospital, Omaha, NE, USA.
Pamela E May-WeeksCollege of Medicine, University of Nebraska Medical Center (UNMC), Omaha, NE, USA.
Rachel K SpoonerInstitute for Human Neuroscience, Boys Town National Research Hospital, Omaha, NE, USA.
Tony W WilsonInstitute for Human Neuroscience, Boys Town National Research Hospital, Omaha, NE, USA. tony.wilson@boystown.org.ORCID http://orcid.org/0000-0002-5053-8306

Funding

Stress-Induced Aberrations in the Mitochondrial Redox Environment Impact Developing Neural Circuits Supporting Cognitive ControlP20GM144641 · NIGMS · FATHER FLANAGAN'S BOYS' HOME · PI Giorgia Picci · 2022 to 2026
$15.1M
Suppression of Pathological Spontaneous Cortical Dynamics and Inflammation in NeuroHIVR01DA056223 · NIDA · FATHER FLANAGAN'S BOYS' HOME · PI Tony W. Wilson · 2022 to 2026
$3.4M
THE PROGRESSIVE ELEVATION OF SPONTANEOUS CORTICAL ACTIVITY IN HAND (PESCAH) PROJECTR01MH116782 · NIMH · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI WILSON, TONY W · 2018 to 2022
$3.4M
THE IMPACT OF SPONTANEOUS CORTICAL ACTIVITY ON NEURAL OSCILLATIONS AND BEHAVIORAL PERFORMANCE: EVIDENCE FROM HIGH-DEFINITION TDCS AND MEGRF1MH117032 · NIMH · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI WILSON, TONY W · 2018 to 2018
$2.4M
Next-Generation MEG Imaging for Quantifying Cortical-Subcortical Dynamics in the Context of HIV and Cannabis UseR01DA059542 · NIDA · FATHER FLANAGAN'S BOYS' HOME · PI Tony W. Wilson · 2024 to 2026
$1.9M
Impact of HIV and Cannabis Use on Executive Brain Function and InflammationF31DA063403 · NIDA · FATHER FLANAGAN'S BOYS' HOME · PI Kellen M McDonald · 2025 to 2026
$100k
Foundation for the National Institutes of Health F31-DA063403Foundation for the National Institutes of Health P20-GM144641Foundation for the National Institutes of Health R01-DA056223Foundation for the National Institutes of Health R01-DA059542Foundation for the National Institutes of Health R01-MH116782NIDA NIH HHS F31 DA063403NIDA NIH HHS R01 DA056223NIDA NIH HHS R01 DA059542NIGMS NIH HHS P20 GM144641NIMH NIH HHS R01 MH116782NIMH NIH HHS RF1 MH117032
6 · The paper itself

Abstract

Hippocampal volume is associated with memory and is critical in Alzheimer's disease, but few studies have examined hippocampal subfield volume changes during healthy aging. Herein, we utilize submillimeter MRI to examine age- and sex-specific subfield volumetric changes in 206 participants (M

Indexed as

CognitionEstradiolHippocampal volumeNeuroprotective effectsSex differencesT2-weighted MRI

Identifiers

PMID42315716

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.