ArticleJournal of bone metabolism2026
Muscle Mass, Adiposity, and Bone Health in Surgical Care Setting: A Cross-Sectional Study.
Article in Journal of bone metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOsteoporosis and sarcopenia are interrelated conditions that significantly affect surgical outcomes by impairing bone strength, mobility, and postoperative recovery. Understanding how body composition and metabolic factors influence bone mineral density (BMD) is essential for improving perioperative risk assessment and rehabilitation. This study aimed to evaluate the relationships between regional muscle mass, fat mass (FM), and circulating adipokines with BMD.
methodsA cross-sectional study was conducted in 199 patients. Whole-body dual energy X-ray absorptiometry (DXA) was used to assess regional lean and FM and BMD at multiple skeletal sites. Serum leptin and adiponectin were measured by enzyme-linked immunosorbent assay. Correlations were examined using Pearson's coefficients, and stepwise multiple linear regression identified independent predictors of T-score.
resultsTrunk and gynoid muscle mass exhibited the strongest positive correlations with T-score (r=0.490 and r=0.475, both P<0.001). FM showed weaker associations, while adiponectin correlated inversely with BMD (r=-0.196, P=0.005). In multivariable analysis, trunk muscle mass (β=0.48, P<0.001), gynoid muscle mass (β=0.36, P=0.002), body mass index (β=0.18, P=0.031), and adiponectin (β=-0.22, P=0.008) remained independent predictors (adjusted R²=0.45).
conclusionsSkeletal muscle, particularly in the trunk and hip regions, is the primary determinant of bone density, while adiponectin negatively influences BMD. Incorporating muscle mass assessment and metabolic optimization into perioperative care may enhance fixation stability and postoperative recovery.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.