Evidence map›Paper›PMID 42317366›Full record

ArticleFrontiers in immunology2026

A proteome-wide atlas of humoral immunity to

Mehak Z Khan, Edward B Irvine, Deniz Cizmeci, Leela R L Davies, Arlo Z Randall, Jozelyn Pablo, Samuel J Vidal, Ninaad Lasrado, Patricia A Darrah, Jeff C Hsiao and 15 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Mehak Z Khan *Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, United States.
Edward B Irvine *Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, United States.
Deniz Cizmeci *Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, United States.
Leela R L DaviesRagon Institute of MGH, MIT and Harvard, Cambridge, MA, United States.
Arlo Z RandallAntigen Discovery Inc., Irvine, CA, United States.
Jozelyn PabloAntigen Discovery Inc., Irvine, CA, United States.
Samuel J VidalBeth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States.
Ninaad LasradoBeth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States.
Patricia A DarrahVaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD, United States.
Jeff C HsiaoRagon Institute of MGH, MIT and Harvard, Cambridge, MA, United States.
Colin MannRagon Institute of MGH, MIT and Harvard, Cambridge, MA, United States.
Shreya NairRagon Institute of MGH, MIT and Harvard, Cambridge, MA, United States.
Patricia S GraceRagon Institute of MGH, MIT and Harvard, Cambridge, MA, United States.
Laura FontanaRagon Institute of MGH, MIT and Harvard, Cambridge, MA, United States.
Boris JuelgRagon Institute of MGH, MIT and Harvard, Cambridge, MA, United States.
Dan H BarouchBeth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States.
Blanca I RestrepoSchool of Public Health, University of Texas Health Science Center at Houston, Brownsville, TX, United States.
Mario RoedererVaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD, United States.
Robert A SederVaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD, United States.
Robert S WallisThe Aurum Institute, Johannesburg, South Africa.
Gavin ChurchyardThe Aurum Institute, Johannesburg, South Africa.
Catherine M SteinDepartment of Medicine, Case Western Reserve University, Cleveland, OH, United States.
W Henry BoomDepartment of Medicine, Case Western Reserve University, Cleveland, OH, United States.
Joseph J CampoAntigen Discovery Inc., Irvine, CA, United States.
Galit AlterRagon Institute of MGH, MIT and Harvard, Cambridge, MA, United States.

Funding

IMMUNE MECHANISMS OF PROTECTION AGAINST MYCOBACTERIUM TUBERCULOSIS CENTER (IMPAC-TB)75N93019C00071 · NIAID · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI FORTUNE, SARAH · 2019 to 2025
$57.3M
Systems Pharmacology of Therapeutic and Adverse Responses to ImmuneCheckpoint and Small Molecule DrugsU54CA225088 · NCI · HARVARD MEDICAL SCHOOL · PI SHARPE, ARLENE H. · 2018 to 2022
$10.8M
Omic and Multidimensional Spatial Atlas of Metastatic Breast CancerU2CCA233280 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI GOECKS, JEREMY · 2018 to 2023
$9.7M
Pre-cancer atlases of cutaneous and hematologic origin (PATCH Center)U2CCA233262 · NCI · HARVARD MEDICAL SCHOOL · PI SANTAGATA, SANDRO · 2018 to 2023
$8.7M
Exploiting Fc-engineering to dissect mechanisms of anti-microbial action of M. tuberculosis-specific antibodiesF31AI150171 · NIAID · HARVARD SCHOOL OF PUBLIC HEALTH · PI IRVINE, EDWARD BUFORD · 2020 to 2021
$64k
NCI NIH HHS U2C CA233262NCI NIH HHS U2C CA233280NCI NIH HHS U54 CA225088NIAID NIH HHS F31 AI150171NIH HHS 75N93019C00071
6 · The paper itself

Abstract

Exposure to

Indexed as

Antibodies, BacterialImmunity, HumoralMycobacterium tuberculosisProteomeTuberculosisAnimalsAntigens, BacterialBacterial ProteinsHumansLatent TuberculosisProteomicsAntibodies, BacterialAntigens, BacterialBacterial ProteinsProteomeantibodiesantigensmicroarrayMycobacterium tuberculosisproteomeserologyvaccines

Identifiers

PMID42317366
PMCPMC13271977

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.