Evidence map›Paper›PMID 42317752›Full record

ReviewFrontiers in microbiology2026

Pro-inflammatory microbiota mediates the effect of host risk genes in Crohn's disease.

Dawei Gong, Shanshan Zhang, Heng Zhu, Jicai Lv, Liguo Sun, Ziying Chen, Leisheng Zhang, Shumin Zhang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dawei Gong *Department of Gastroenterology and Endoscopy Center, The Fourth People's Hospital of Jinan, Jinan, China.
Shanshan Zhang *Shandong Provincial Key Medical and Health Laboratory of Blood Ecology and Biointelligence, Jinan Key Laboratory of Medical Cell Bioengineering, Science and Technology Innovation Center, The Fourth People's Hospital of Jinan Affiliated to Shandong Second Medical University, Jinan, China.
Heng Zhu *Department of Quality Management, The Fourth People's Hospital of Jinan Affiliated to Shandong Second Medical University, Jinan, China.
Jicai LvDepartment of Hepatology II, Shandong Public Health Clinical Center, Shandong University, Jinan, China.
Liguo SunDepartment of Gastroenterology and Endoscopy Center, The Fourth People's Hospital of Jinan, Jinan, China.
Ziying ChenShandong Provincial Key Medical and Health Laboratory of Blood Ecology and Biointelligence, Jinan Key Laboratory of Medical Cell Bioengineering, Science and Technology Innovation Center, The Fourth People's Hospital of Jinan Affiliated to Shandong Second Medical University, Jinan, China.
Leisheng ZhangShandong Provincial Key Medical and Health Laboratory of Blood Ecology and Biointelligence, Jinan Key Laboratory of Medical Cell Bioengineering, Science and Technology Innovation Center, The Fourth People's Hospital of Jinan Affiliated to Shandong Second Medical University, Jinan, China.
Shumin ZhangDepartment of Gastroenterology and Endoscopy Center, The Fourth People's Hospital of Jinan, Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Crohn's disease (CD) is a chronic inflammatory disease mainly characterized by chronic and relapsing intestinal inflammation. The pathogenesis of CD involves dysregulation of the immune response to commensal gut pro-inflammatory microbiota. Genome-wide association studies (GWAS) identified many genetic susceptibility loci associated with CD, such as

Indexed as

Crohn’s diseasegeneticsgenome-wide association studiesinflammationmicrobiota

Identifiers

PMID42317752
PMCPMC13272376

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.